DRC1 Antibodies

AND DRC1 ELISA kits, DRC1 Proteins

Many biological assays use antibodies to detect DRC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DRC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DRC1 antibodies...

We validate the specificity of these antibodies to DRC1 by testing them on tissues known to express DRC1 positively and negatively. Browse below to find the DRC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DRC1 Infographic by Boster Bio

All DRC1 Products

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Specificity

Applications

Price

DRC1 (NM_145038) Human Recombinant Protein

$813
Cat # PROTQ96MC2
20 µg

DRC1 (NM_145038) Human Over-expression Lysate

Human

$960
Cat # LS092749
100 µg

DRC1 Overview

Facts about Dynein regulatory complex protein 1.

DRC1 3D structure. Source: alphafold

Dynein regulatory complex protein 1 (DRC1)

Part of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and modulates microtubule sliding in motile axonemes (By similarity). Plays a crucial role in the assembly of N-DRC and stabilizes the assembly of multiple inner dynein arms and radial spokes.

Coassembles with CCDC65/DRC2 to form a central scaffold required for assembly of the N-DRC and its attachment to the outer doublet microtubules (PubMed:23354437). .

Gene Information

Human
Gene Name:	DRC1
Uniprot:	Q96MC2
Entrez:	92749

Family

Belongs to:

DRC1 family

Alternative Names

Dynein regulatory complex protein 1

Molecular Weight

Mass (kDA):
87.134 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (26401920..26456713)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.

Diseases

Ciliary dyskinesia, primary, 21 (CILD21)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DRC1

References

PMID: 23354437 by Wirschell M., et al. The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans.

PMID: 25186273 by Raidt J., et al. Ciliary beat pattern and frequency in genetic variants of primary ciliary dyskinesia.