DNTT Antibodies

AND DNTT ELISA kits, DNTT Proteins

Many biological assays use antibodies to detect DNTT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNTT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNTT antibodies...

We validate the specificity of these antibodies to DNTT by testing them on tissues known to express DNTT positively and negatively. Browse below to find the DNTT antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DNTT Infographic by Boster Bio

All DNTT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TdT/DNTT Antibody Picoband®

10 Citations 16 Q&As

Human

$370
Cat # PB9162
100 μg/vial

Anti-TDT DNTT Monoclonal Antibody

1 Citations 15 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M05546
100 μl

Anti-Terminal deoxynucleotidyl transferase (TdT) DNTT Rabbit Monoclonal Antibody, Clone#RM379

1 Citations 5 Q&As

Human

IHC, WB

$431
Cat # M05546-1
100uL

TdT (DNTT) (NM_004088) Human Over-expression Lysate

Human

$628
Cat # LS001791
100 µg

DNTT Overview

Facts about DNA nucleotidylexotransferase.

DNTT 3D structure. Source: alphafold

DNA nucleotidylexotransferase (DNTT)

Template-independent DNA polymerase which catalyzes the random inclusion of deoxynucleoside 5'-triphosphate into the 3'-end of a DNA initiator. One of the in vivo functions of the enzyme is that the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Gene Information

Human
Gene Name:	DNTT
Uniprot:	P04053
Entrez:	1791

Family

Belongs to:

DNA polymerase type-X family

Alternative Names

deoxynucleotidyltransferase, terminal; DNTT; EC 2.7.7; EC 2.7.7.31; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TdT; TDTDNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; Terminal transferase

Molecular Weight

Mass (kDA):
58.536 kDA

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (96304434..96338564)

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Sclerosis
Cell Transformation, Neoplastic
Congenital Abnormality
Leukemia, T-cell
Multiple Sclerosis
Nervous System Disorder
Precursor T-cell Lymphoblastic Leukemia-lymphoma

Multiple Sclerosis, Relapsing-remitting
Malignant Neoplasms
Steroid Sulfatase Deficiency Disease
Dysmyelopoietic Syndromes

Interacting Proteins

Pathways

Methylation
Gene Silencing
Pathogenesis
Transport
Cell Development
Dna Methylation
Histone Modification

Histone Methylation
Chromatin Assembly

PTMs

Methylation

Deacetylation

Research Areas

Adaptive Immunity
Cell Cycle and Replication
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNTT

References

PMID: 2863268 by Peterson R.C., et al. Expression of human terminal deoxynucleotidyl transferase in Escherichia coli.

PMID: 2833741 by Riley L.K., et al. Human terminal deoxyribonucleotidyltransferase: molecular cloning and structural analysis of the gene and 5' flanking region.

10 Publications of Boster DNTT Antibodies & ELISA Kits

PubMed ID: 28186502, Jiang Y, Yu M, Hu X, Han L, Yang K, Ba H, Zhang Z, Yin B, Yang XP, Li Z, Wang J....
PubMed ID: 24649049, Zhang R, Pei H, Ru L, Li H, Liu G. Biomed Rep. 2013 Nov;1(6):895-900. Epub 2013 ...
PubMed ID: 15621629, Xu Bb, Liu Cq, Gao X, Zhang Wq, Wang Sw, Cao Yl. J Asian Nat Prod Res. 2005 Jun;...
PubMed ID: 23002367, Gong Wh, Zheng Wx, Wang J, Chen Sh, Pang B, Hu Xm, Cao Xl. World J Gastroenterol...
PubMed ID: 23631820, Zeng C, Ke Z, Song Y, Yao Y, Hu X, Zhang M, Li H, Yin J. Exp Mol Pathol. 2013 Au...
PubMed ID: 24303082, Xi D, Wang M, Ye H, Luo X, Ning Q. Plos One. 2013 Nov 26;8(11):E82330. Doi: 10.1...
PubMed ID: 24448360, Yang Q, Zhang F, Ding Y, Huang J, Chen S, Wu Q, Wang Z, Wang Z, Chen C. Br J Can...
PubMed ID: 15920191, Luo T, Xia Z, Ansley Dm, Ouyang J, Granville Dj, Li Y, Xia Zy, Zhou Qs, Liu Xy. ...
PubMed ID: 16790636, Luo T, Xia Z. Anesth Analg. 2006 Jul;103(1):110-6, Table Of Contents. A Small Do...
PubMed ID: 23131582, Tochinai R, Ando M, Suzuki T, Suzuki K, Nagata Y, Hata C, Uchida K, Kobayashi T,...

*More publications can be found for each product on its corresponding product page