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- Table of Contents
Facts about Deoxyribonuclease-2-alpha.
Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. .
Human | |
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Gene Name: | DNASE2 |
Uniprot: | O00115 |
Entrez: | 1777 |
Belongs to: |
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DNase II family |
Acid DNase; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2A; DNL; DNL2; EC 3.1.22.1; Lysosomal DNase II; R31240_2
Mass (kDA):
39.581 kDA
Human | |
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Location: | 19p13.13 |
Sequence: | 19; NC_000019.10 (12875209..12881449, complement) |
Lysosome.
PMID: 9924608 by Yasuda T., et al. Structure and organization of the human deoxyribonuclease II (DNase II) gene.
PMID: 9647784 by Shiokawa D., et al. Cloning of cDNAs encoding porcine and human DNase II.