DGKG Antibodies

AND DGKG ELISA kits, DGKG Proteins

Many biological assays use antibodies to detect DGKG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DGKG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DGKG antibodies...

We validate the specificity of these antibodies to DGKG by testing them on tissues known to express DGKG positively and negatively. Browse below to find the DGKG antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DGKG Infographic by Boster Bio

All DGKG Products

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Applications

Price

DGKG (NM_001080745) Human Recombinant Protein

$1062
Cat # PROTP49619
20 µg

DGKG (NM_001080744) Human Over-expression Lysate

Human

$960
Cat # LS001608
100 µg

DGKG Overview

Facts about Diacylglycerol kinase gamma.

DGKG 3D structure. Source: alphafold

Diacylglycerol kinase gamma (DGKG)

Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. .

Gene Information

Human
Gene Name:	DGKG
Uniprot:	P49619
Entrez:	1608

Family

Belongs to:

eukaryotic diacylglycerol kinase family

Alternative Names

DAG kinase gamma; DAGK3; DAGK3MGC104993; DGKG; DGKgamma; DGK-gamma; diacylglycerol kinase gamma; diacylglycerol kinase, gamma (90kD); diacylglycerol kinase, gamma 90kDa; diacylglyerol kinase gamma; Diglyceride kinase gamma; EC 2.7.1.107; MGC133330

Molecular Weight

Mass (kDA):
89.124 kDA

Genomic Context


Human

Location:	3q27.2-q27.3
Sequence:	3; NC_000003.12 (186147201..186362234, complement)

Tissue Specificity

Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma.

Subcellular Localizations

Cytoplasm. Membrane. Can be loosely bound to the membranes.

Diseases

Urticaria
Obesity
Encephalitis
Hiv Infections
Inflammation
Infarction
Heart Failure
Cardiac Hypertrophy
Pediatric Obesity
Tissue Adhesions
Childhood Asthma
Diabetes Mellitus

Chronic Eosinophilic Leukemia
Inflammatory Response
Diabetic Cardiomyopathies
Diabetes Mellitus, Non-insulin-dependent
Myocardial Infarction
Cardiomyopathies
Malignant Neoplasms

Pathways

Regulation Of Biological Process
Cognition
Cell Projection Organization
Cell Proliferation
Developmental Process
Cell Development
Proteolysis
Cellular Process
Negative Regulation Of Cell Proliferation
Biosynthetic Process
Positive Regulation Of Cellular Process
Defense Response
Inflammatory Response

Regulation Of Cellular Process
Metabolic Process
Cell Cycle
Axon Guidance
Positive Regulation Of Biological Process
Regulation Of Cell Proliferation
Negative Regulation Of Biological Process

PTMs

Acetylation

Research Areas

Lipid and Metabolism
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGKG

References

PMID: 8034597 by Kai M., et al. Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells.

PMID: 10071200 by Stoehr H., et al. Mapping and genomic characterization of the gene encoding diacylglycerol kinase gamma (DAGK3): assessment of its role in dominant optic atrophy (OPA1).