DGKQ Antibodies

AND DGKQ ELISA kits, DGKQ Proteins

Many biological assays use antibodies to detect DGKQ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DGKQ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DGKQ antibodies...

We validate the specificity of these antibodies to DGKQ by testing them on tissues known to express DGKQ positively and negatively. Browse below to find the DGKQ antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DGKQ Infographic by Boster Bio

All DGKQ Products

Product

Figures

Specificity

Applications

Price

DGKQ Colorimetric Cell-Based ELISA

Human

ELISA

$480
Cat # EKC1748
1 kit, containing one 96-well plate and all necessary reagents

Anti-DGK-Theta (S725) DGKQ Antibody

Human

IHC

$405
Cat # A08705S725
100ul

Anti-DGK-theta DGKQ Antibody

Human

ELISA, IHC, WB

$380
Cat # A08705
100ul

DAGK (DGKQ) (NM_001347) Human Over-expression Lysate

Human

$628
Cat # LS001609
100 µg

DGKQ Overview

Facts about Diacylglycerol kinase theta.

DGKQ 3D structure. Source: alphafold

Diacylglycerol kinase theta (DGKQ)

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids.

Activated from the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP- induced activation of NR5A1 and subsequent steroidogenic gene transcription by providing PA as ligand for NR5A1.

Gene Information

Human
Gene Name:	DGKQ
Uniprot:	P52824
Entrez:	1609

Family

Belongs to:

eukaryotic diacylglycerol kinase family

Alternative Names

DAG kinase theta; DAGK; DAGK4EC 2.7.1.107; DAGK7; DGKQ; DGKtheta; DGK-theta; diacylglycerol kinase theta; diacylglycerol kinase, theta (110kD); diacylglycerol kinase, theta 110kDa; Diglyceride kinase theta

Molecular Weight

Mass (kDA):
101.155 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (958887..973569, complement)

Subcellular Localizations

Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Nucleus. Nucleus speckle. Translocates to the nucleus in response to thrombin stimulation (PubMed:15632189). Translocates to the plasma membrane in response to steroid hormone receptor stimulation (PubMed:15632189). Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH (PubMed:15632189).

Diseases

Parkinson Disease
Dysequilibrium Syndrome

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGKQ

References

PMID: 7607687 by Pilz A., et al. Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene.

PMID: 10066731 by Houssa B., et al. Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.