DDX6 Antibodies

AND DDX6 ELISA kits, DDX6 Proteins

Many biological assays use antibodies to detect DDX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDX6 antibodies...

We validate the specificity of these antibodies to DDX6 by testing them on tissues known to express DDX6 positively and negatively. Browse below to find the DDX6 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DDX6 Infographic by Boster Bio

All DDX6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DDX6 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03826
100ul

Anti-DDX6 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03826-1
100 μg/vial

DDX6 (NM_004397) Human Recombinant Protein

$1062
Cat # PROTP26196
20 µg

Anti-DDX6 Antibody Picoband® (monoclonal, 8G6)

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M03826-1
100 μg/vial

Anti-DDX6 Mouse Monoclonal Antibody [Clone ID: OTI2D6]

Human, Mouse, Rat

IHC, WB

$523
Cat # M03826
100 µl

Anti-DDX6 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M03826-2
100 μl/vial

DDX6 (NM_004397) Human Over-expression Lysate

Human

$628
Cat # LS001656
100 µg

DDX6 Overview

Facts about Probable ATP-dependent RNA helicase DDX6.

DDX6 3D structure. Source: alphafold

Probable ATP-dependent RNA helicase DDX6 (DDX6)

In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich states by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573).

Gene Information

Human
Gene Name:	DDX6
Uniprot:	P26196
Entrez:	1656

Family

Belongs to:

DEAD box helicase family

Alternative Names

ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); EC 3.6.1; EC 3.6.4.13; FLJ36338; HLR2DEAD box-6; Oncogene RCK; probable ATP-dependent RNA helicase DDX6; RCKP54

Molecular Weight

Mass (kDA):
54.417 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (118747763..118791696, complement)

Tissue Specificity

Abundantly expressed in most tissues.

Subcellular Localizations

Cytoplasm, P-body. Cytoplasm. Nucleus. Upon cellular stress, relocalizes to stress granules (PubMed:26184334).

Diseases

Neoplasms
Lymphoma
Chromosomal Translocation
Malignant Neoplasms
B-cell Lymphomas
Malignant Paraganglionic Neoplasm
Carcinogenesis
Hepatitis
Hepatitis C
Cell Transformation, Neoplastic
Neuroblastoma
Myeloid Leukemia

Liver Carcinoma
Colorectal Neoplasms
Hiv Infections
Leukemia
Adenoma
Ataxia
Malignant Tumor Of Colon

Interacting Proteins

AES
AGO2
ATXN2
BIRC7
CALCOCO2

CEP70
DCP1A
EDC3
EIF4ENIF1
GOLGA2

IKZF1
KRT40
KRTAP10-8
PNMA5
RUNDC3A

TCF4
TRIM27
TRIM37
VPS52
ZBTB8A

ZNF24

Pathways

Translation
Localization
Mrna Processing
Cell Proliferation
Rna Interference
Gene Silencing
S Phase
Cell Growth
Pathogenesis
Ribosome Assembly
Sexual Reproduction
Nuclear Export
Cell Cycle Arrest

Cell Cycle
Meiosis
Oocyte Maturation
Methylation
Rna Processing
Regulation Of Translation
Viral Replication

PTMs

Cleavage

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDX6

References

PMID: 1579499 by Lu D., et al. Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3.

PMID: 1394235 by Akao Y., et al. The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations.