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DDIT3 Antibodies
AND DDIT3 ELISA kits, DDIT3 Proteins
Many biological assays use antibodies to detect DDIT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDIT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDIT3 antibodies...
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DDIT3 Infographic by Boster Bio
All DDIT3 Products
Product
Figures
Specificity
Applications
Price
Anti-CHOP DDIT3 Monoclonal Antibody
2 Citations 1 Q&As
Human, Mouse, Rat
IHC, WB
$399
Cat # A00311-1
100μl
Cat # A00311-1
100μl
Anti-DDIT3/Chop Rabbit Monoclonal Antibody
4 Citations 3 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M00311
100 μl
Cat # M00311
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1609
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1609
1 kit, containing one 96-well plate and all necessary reagents
Anti-DDIT3 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00311-2
100 μg/vial
Cat # A00311-2
100 μg/vial
Anti-Ddit3 Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00311-4
100 μg/vial
Cat # A00311-4
100 μg/vial
DDIT3 Overview
Facts about DDIT3 upstream open reading frame protein.
DDIT3 upstream open reading frame protein (DDIT3)
Plays an important role in the response to a vast array of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of different genes.
Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of their C/EBP family, impairs their affiliation with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L.
Gene Information
| Human | |
|---|---|
| Gene Name: | DDIT3 |
| Uniprot: | P0DPQ6 |
| Entrez: | 1649 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C/EBP-homologous protein 10; C/EBP-homologous protein; CCAAT/enhancer-binding protein homologous protein; CEBP zeta; CHOP; CHOP10 CEBPZ; CHOP10; CHOP-10; CHOPC/EBP zeta; DDIT3; DDIT-3; DNA damage-inducible transcript 3 protein; DNA-damage-inducible transcript 3; GADD153; Growth arrest and DNA damage-inducible protein GADD153
Molecular Weight
Mass (kDA):
4.284 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3 |
| Sequence: | 12; NC_000012.12 (57516588..57520517, complement) |
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Endoplasmic Reticulum Stress
- Malignant Neoplasms
- Neoplasms
- Growth Arrest
- Physiological Stress
- Carcinoma
- Liposarcoma
- Liposarcoma, Myxoid
- Diabetes Mellitus
- Malignant Paraganglionic Neoplasm
- Leukemia
- Liver Carcinoma
Pathways
- Cell Death
- Cell Cycle
- Translation
- Pathogenesis
- Cell Growth
- Cell Proliferation
- Induction Of Apoptosis
- Cell Cycle Arrest
- Localization
- Secretion
- Autophagy
- Dna Repair
- Transport
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Ubiquitination
- Methylation
- Glycosylation
- Oxidation
Research Areas
- Apoptosis
- Cell Cycle and Replication
- DNA Repair
- Hypoxia
- Lipid and Metabolism
- Neuroscience
- Unfolded Protein Response
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDIT3
bosterbio.com/bosterbio-gene-info-cards/DDIT3
References
PMID: 29083303 by Samandi S., et al. Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins.
7 Publications of Boster DDIT3 Antibodies & ELISA Kits
- PubMed ID: 10.4103/1673-5374.153698, Ulinastatin suppresses endoplasmic reticulum stress and apoptosis in the hippoca...
- PubMed ID: 10.3892/ol.2013.1651, Endoplasmic reticulum stress in diethylnitrosamine‑induced rat liver cancer
- PubMed ID: 10.3892/mmr.2019.10175, Effect of endoplasmic reticulum stress involved in manganese‑induced neurotoxi...
- PubMed ID: 10.1042/BSR20190578, Tension induces intervertebral disc degeneration via endoplasmic reticulum stres...
- PubMed ID: 10.1016/j.physbeh.2021.113312, The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hipp...
- PubMed ID: 33412188, Binayi F,Zardooz H,Ghasemi R,Hedayati M,Askari S,Pouriran R,Sahraei M.The chemic...
- PubMed ID: 21625440, Ding Y, Zou J, Li Z, Tian J, Abdelalim S, Du F, She R, Wang D, Tan C, Wang H, Ch...
*More publications can be found for each product on its corresponding product page