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- Table of Contents
Facts about DDB1- and CUL4-associated factor 12.
Human | |
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Gene Name: | DCAF12 |
Uniprot: | Q5T6F0 |
Entrez: | 25853 |
Belongs to: |
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WD repeat DCAF12 family |
DDB1- and CUL4-associated factor 12; CT102; DDB1 and CUL4 associated factor 12; KIAA1892; TCC52; WDR40A
Mass (kDA):
50.517 kDA
Human | |
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Location: | 9p13.3 |
Sequence: | 9; NC_000009.12 (34086387..34126698, complement) |
Highly expressed in lung cancer tissues and some cancer cell lines. Restricted expression in normal testis.
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
PMID: 16949367 by Jin J., et al. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.
PMID: 16964240 by Angers S., et al. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.