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- Table of Contents
Facts about Cation channel sperm-associated protein subunit zeta.
Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization within the mammalian female reproductive tract. .
Human | |
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Gene Name: | CATSPERZ |
Uniprot: | Q9NTU4 |
Entrez: | 25858 |
Belongs to: |
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No superfamily |
Cation channel sperm-associated protein subunit zeta
Mass (kDA):
22.839 kDA
Human | |
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Location: | 11q13.1 |
Sequence: | 11; NC_000011.10 (64300358..64304770) |
Cell projection, cilium, flagellum membrane; Peripheral membrane protein. Specifically located in the principal piece of sperm tail (PubMed:28226241). Although it does not contain a transmembrane domain, localizes with the CatSper complex at the flagellum membrane (PubMed:28226241).
PMID: 28226241 by Chung J.J., et al. CatSperzeta regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility.