Protein DBF4 homolog B Antibodies

AND DBF4B ELISA kits, Protein DBF4 homolog B Proteins

Many biological assays use antibodies to detect Protein DBF4 homolog B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein DBF4 homolog B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein DBF4 homolog B antibodies...

We validate the specificity of these antibodies to Protein DBF4 homolog B by testing them on tissues known to express DBF4B positively and negatively. Browse below to find the DBF4B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DBF4B Infographic by Boster Bio

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DBF4B (NM_145663) Human Over-expression Lysate

Human

$960
Cat # LS080174
100 µg

DBF4B Overview

Facts about Protein DBF4 homolog B.

DBF4B 3D structure. Source: alphafold

Protein DBF4 homolog B (DBF4B)

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases.

The intricate CDC7-DBF4B selectively phosphorylates MCM2 subunit in'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. .

Gene Information

Human
Gene Name:	DBF4B
Uniprot:	Q8NFT6
Entrez:	80174

Family

Belongs to:

No superfamily

Alternative Names

Activator of S phase kinase-like protein 1; activator of S-phase kinase-like protein 1; ASKL1CHIFB; ASK-like protein 1; chifb; Chiffon homolog B; DBF4 homolog B (S. cerevisiae); Dbf4-related factor 1; DRF1MGC15009; FLJ13087; protein DBF4 homolog B; ZDBF1B; zinc finger, DBF-type containing 1B

Molecular Weight

Mass (kDA):
67.243 kDA

Genomic Context


Human

Location:	17q21.31\|17q21
Sequence:	17; NC_000017.11 (44708581..44752732)

Tissue Specificity

Widely expressed. Highly expressed in testis.

Subcellular Localizations

Nucleus. Predominantly found in soluble fraction but not in the chromatin-bound fraction.

Interacting Proteins

LMO2
ROPN1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DBF4B

References

PMID: 12065429 by Montagnoli A., et al. Drf1, a novel regulatory subunit for human Cdc7 kinase.

PMID: 15668232 by Yoshizawa-Sugata N., et al. A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases.