DAZ2 Antibodies

AND DAZ2 ELISA kits, DAZ2 Proteins

Many biological assays use antibodies to detect DAZ2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DAZ2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DAZ2 antibodies...

We validate the specificity of these antibodies to DAZ2 by testing them on tissues known to express DAZ2 positively and negatively. Browse below to find the DAZ2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DAZ2 Infographic by Boster Bio

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DAZ2 Overview

Facts about Deleted in azoospermia protein 2.

DAZ2 3D structure. Source: alphafold

Deleted in azoospermia protein 2 (DAZ2)

RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.

Gene Information

Human
Gene Name:	DAZ2
Uniprot:	Q13117
Entrez:	57055

Family

Belongs to:

RRM DAZ family

Alternative Names

deleted in azoospermia 2; deleted in azoospermia protein 2; MGC126442

Molecular Weight

Mass (kDA):
63.111 kDA

Genomic Context


Human

Location:	Yq11.223
Sequence:	Y; NC_000024.10 (23219457..23291356)

Tissue Specificity

Testis specific.

Subcellular Localizations

Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.

Diseases

Oligospermia
Infertility
Azoospermia
Male Infertility
Congenital Absence Of Germinal Epithelium Of Testes
Steroid Sulfatase Deficiency Disease
Sex Chromosome Aberrations
Spermatogenesis Arrest
Chromosome Inversion

Partial Deletion Of Y
Sex Chromosome Disorders Of Sex Development
Cytogenetic Abnormality
Growth Arrest

Pathways

Spermatogenesis
Transport
Gene Conversion
Translation
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DAZ2

References

PMID: 7670487 by Reijo R.A., et al. Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

PMID: 10936047 by Saxena R., et al. Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.