CYP11A1 Antibodies

AND CYP11A1 ELISA kits, CYP11A1 Proteins

Many biological assays use antibodies to detect CYP11A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP11A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP11A1 antibodies...

We validate the specificity of these antibodies to CYP11A1 by testing them on tissues known to express CYP11A1 positively and negatively. Browse below to find the CYP11A1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP11A1 Infographic by Boster Bio

All CYP11A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-CYP11A1 Antibody Picoband®

1 Citations 5 Q&As

Human

IHC, WB

$370
Cat # PA1698
100 μg/vial

Anti-CYP11A1 Antibody Picoband®

1 Citations 16 Q&As

Mouse, Rat

$370
Cat # PA1698-1
100 μg/vial

Anti-CYP11A1 Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A01071
100ul

Anti-CYP11A1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01071-1
100ul

CYP11A1 (NM_001099773) Human Recombinant Protein

$813
Cat # PROTP05108
20 µg

Anti-CYP11A1 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A01071-2
100 μg/vial

CYP11A1 Overview

Facts about Cholesterol side-chain cleavage enzyme, mitochondrial.

CYP11A1 3D structure. Source: alphafold

Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1)

Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone, the precursor of most steroid hormones. .

Gene Information

Human
Gene Name:	CYP11A1
Uniprot:	P05108
Entrez:	1583

Family

Belongs to:

cytochrome P450 family

Alternative Names

Cholesterol desmolase; cholesterol monooxygenase (side-chain-cleaving); cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1; cytochrome P450C11A1; EC 1.14.15; EC 1.14.15.6; steroid 20-22-lyase; subfamily XIA (cholesterol side chain cleavage)

Molecular Weight

Mass (kDA):
60.102 kDA

Genomic Context


Human

Location:	15q24.1
Sequence:	15; NC_000015.10 (74337762..74367646, complement)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein. Localizes to the matrix side of the mitochondrion inner membrane.

Diseases

Malignant Neoplasms
Neoplasms
Polycystic Ovary Syndrome
Adrenal Gland Hypofunction
Hyperplasia
Infertility
Pituitary Diseases
Hypertensive Disease
Disorders Of Sex Development
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Malignant Neoplasm Of Breast

Adrenal Hyperplasia
Ovarian Neoplasm
Mammary Neoplasms
Tumors Of Adrenal Cortex
Congenital Adrenal Hyperplasia
Congenital Abnormality
Carcinoma

Pathways

Secretion
Transport
Luteinization
Ovulation
Cell Proliferation
Localization
Cholesterol Transport
Progesterone Secretion
Spermatogenesis
Cell Differentiation
Fertilization
Cortisol Secretion
Cell Cycle

Oocyte Maturation
Pathogenesis
Cholesterol Homeostasis
Reverse Transcription
Sex Differentiation
Cell Growth
Cell Development

PTMs

Cleavage
Phosphorylation
Hydroxylation
Reduction

Sumoylation
Methylation
Ubiquitination
Myristoylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP11A1

References

PMID: 3024157 by Chung B.-C., et al. Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.

PMID: 3038854 by Morohashi K., et al. Gene structure of human cytochrome P-450(SCC), cholesterol desmolase.

1 Publications of Boster CYP11A1 Antibodies & ELISA Kits

PubMed ID: 23555723, Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP...

*More publications can be found for each product on its corresponding product page