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- Table of Contents
2 Citations 16 Q&As
2 Citations 5 Q&As
Facts about CD9 antigen.
Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.
Human | |
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Gene Name: | CD9 |
Uniprot: | P21926 |
Entrez: | 928 |
Belongs to: |
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tetraspanin (TM4SF) family |
BA2; BA-2/p24 antigen; BTCC-1; CD9 antigen; CD9 molecule; CD9; Cell growth-inhibiting gene 2 protein; DRAP-27; Leukocyte antigen MIC3; MIC3; motility related protein-1,5H9 antigen; Motility-related protein; MRP-1FLJ99568; p24; tetraspanin-29; TSPAN29; TSPAN-29; TSPAN29MIC3CD9 antigen (p24)
Mass (kDA):
25.416 kDA
Human | |
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Location: | 12p13.31 |
Sequence: | 12; NC_000012.12 (6199946..6238266) |
Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells.
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Secreted, extracellular exosome. Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO.
PMID: 1840589 by Boucheix C., et al. Molecular cloning of the CD9 antigen. A new family of cell surface proteins.
PMID: 2037603 by Lanza F., et al. cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.
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