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CD226 antigen Antibodies
AND CD226 ELISA kits, CD226 antigen Proteins
Many biological assays use antibodies to detect CD226 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD226 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD226 antigen antibodies...
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CD226 Infographic by Boster Bio
All CD226 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1098
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1098
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2229
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2229
1 kit, containing two 96-well plates and all necessary reagents
Human, Monkey, Mouse
ELISA, IF, IHC, WB
$380
Cat # A01094S329
100ul
Cat # A01094S329
100ul
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01094-2
100 μg/vial
Cat # A01094-2
100 μg/vial
Human
ELISA
$499
Cat # EK2161
96 wells/kit, with removable strips.
Cat # EK2161
96 wells/kit, with removable strips.
CD226 Overview
Facts about CD226 antigen.
CD226 antigen (CD226)
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2.
Upon ligand binding, stimulates T- cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).
Gene Information
| Human | |
|---|---|
| Gene Name: | CD226 |
| Uniprot: | Q15762 |
| Entrez: | 10666 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD226 antigenplatelet and T cell activation antigen 1; CD226 molecule; CD226; DNAM1; DNAM-1; DNAM1adhesion glycoprotein; DNAM-1DNAX accessory molecule-1; DNAX accessory molecule 1; PTA1; T lineage-specific activation antigen 1 antigen; TLiSA1
Molecular Weight
Mass (kDA):
38.614 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q22.2 |
| Sequence: | 18; NC_000018.10 (69853274..69962086, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Autoimmune Reaction
- Autoimmune Diseases
- Neoplasms
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Sclerosis
- Arthritis
- Autoimmunity
- Rheumatoid Arthritis
- Malignant Neoplasms
- Multiple Sclerosis
Interacting Proteins
- NECTIN2
- TIGIT
Pathways
- Pathogenesis
- Cell Adhesion
- Secretion
- Cell Activation
- Immune Response
- Cell Differentiation
- T Cell Activation
- Cytokine Secretion
- T Cell Differentiation
- Platelet Activation
- Cell Death
- T Cell Proliferation
- Cell Proliferation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD226
bosterbio.com/bosterbio-gene-info-cards/CD226
References
PMID: 8673704 by Shibuya A., et al. DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes.
PMID: 15039383 by Tahara-Hanaoka S., et al. Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).