Phenylalanine--tRNA ligase, mitochondrial (FARS2)

Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an abbreviated variation of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA into the ribosome and incorporation of ROS-damaged amino acid into proteins.

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