Cytochrome P450 4F3 Antibodies

AND CYP4F3 ELISA kits, Cytochrome P450 4F3 Proteins

Many biological assays use antibodies to detect Cytochrome P450 4F3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 4F3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 4F3 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 4F3 by testing them on tissues known to express CYP4F3 positively and negatively. Browse below to find the CYP4F3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP4F3 Infographic by Boster Bio

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Anti-CP4F3 CYP4F3 Antibody

Human

ELISA, WB

$380
Cat # A03389
100ul

CYP4F3 Overview

Facts about Cytochrome P450 4F3.

CYP4F3 3D structure. Source: alphafold

Cytochrome P450 4F3 (CYP4F3)

Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B(4), a potent chemoattractant for polymorphonuclear leukocytes, it's low action for arachidonic acid. .

Gene Information

Human
Gene Name:	CYP4F3
Uniprot:	Q08477
Entrez:	4051

Family

Belongs to:

cytochrome P450 family

Alternative Names

CYP4F; CYPIVF3; Cytochrome P450 4F3; cytochrome P-450; cytochrome P450, family 4, subfamily F, polypeptide 3; cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omegahydroxylase); Cytochrome P450-LTB-omega; EC 1.14.13.30; leukotriene B4 omega hydroxylase; Leukotriene-B(4) 20-monooxygenase 2; leukotriene-B(4) omega-hydroxylase 2; leukotriene-B4 20-monooxygenase; LTB4HCPF3

Molecular Weight

Mass (kDA):
59.847 kDA

Genomic Context


Human

Location:	19p13.12
Sequence:	19; NC_000019.10 (15640897..15662825)

Tissue Specificity

Isoform CYP4F3A is expressed in the polymorphonuclear leukocytes as well as leukocytes and bone marrow. Isoform CYP4F3B is selectively expressed in liver and kidney and is also the predominant CYP4F isoform in trachea and tissues of the gastrointestinal tract.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Liver Carcinoma
Inflammation
Neoplasms
Leukemia
Malignant Neoplasm Of Breast
Carcinoma
Acute Promyelocytic Leukemia
Celiac Disease
Haematotoxicity
Poisoning
Sclerosis
Adenoma

Inflammatory Bowel Diseases
Malignant Tumor Of Colon
Kidney Neoplasm
Intestinal Diseases
Multiple Sclerosis, Relapsing-remitting
Hemorrhage
Renal Cell Carcinoma

Pathways

Cell Proliferation
Localization
Transport
Translation
Pathogenesis
Protein Phosphorylation
Hepatocyte Differentiation
Immune Response
Dna Repair
Fatty Acid Beta-oxidation
Energy Homeostasis
Cell Cycle Arrest

Cell Division
Drug Transport
Cell Cycle
Lipid Homeostasis
Cell Differentiation
Innate Immune Response

PTMs

Hydroxylation

Oxidation

Phosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP4F3

References

PMID: 8486631 by Kikuta Y., et al. A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes. cDNA cloning and expression of leukotriene B4 omega- hydroxylase.

PMID: 9539102 by Kikuta Y., et al. Human leukotriene B4 omega-hydroxylase (CYP4F3) gene: molecular cloning and chromosomal localization.