Cytochrome P450 4A11 Antibodies

AND CYP4A11 ELISA kits, Cytochrome P450 4A11 Proteins

Many biological assays use antibodies to detect Cytochrome P450 4A11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 4A11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 4A11 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 4A11 by testing them on tissues known to express CYP4A11 positively and negatively. Browse below to find the CYP4A11 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP4A11 Infographic by Boster Bio

All CYP4A11 Products

Product

Figures

Specificity

Applications

Price

Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody

5 Q&As

Human

$360
Cat # A03493
100 µl

Anti-Cytochrome P450 4A Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M03493
100 μl/vial

CYP4A11 Overview

Facts about Cytochrome P450 4A11.

CYP4A11 3D structure. Source: alphafold

Cytochrome P450 4A11 (CYP4A11)

Catalyzes the omega- and (omega-1)-hydroxylation of different fatty acids like laurate, myristate and palmitate. Has little action toward prostaglandins A1 and E1.

Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). .

Gene Information

Human
Gene Name:	CYP4A11
Uniprot:	Q02928
Entrez:	1579

Family

Belongs to:

cytochrome P450 family

Alternative Names

20-HETE synthase; CP4Y; CYP4A2; cytochrome P450 4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; cytochrome P-450HK-omega; cytochrome P450HL-omega; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase; P450HL-omega

Molecular Weight

Mass (kDA):
59.348 kDA

Genomic Context


Human

Location:	1p33
Sequence:	1; NC_000001.11 (46929177..46941476, complement)

Tissue Specificity

Kidney and liver.

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Diseases

Hypertensive Disease
Cholangiocarcinoma
Infarction
Diabetes Mellitus
Malignant Neoplasms
Inflammation
Coronary Artery Disease
Cerebrovascular Accident
Essential Hypertension
Pathologic Vasoconstriction
Liver Carcinoma
Renal Vascular Disorder

Myocardial Infarction
Cardiovascular Diseases
Ischemic Stroke
Hemorrhage
Pathologic Neovascularization
Hypokinesia
Atherosclerosis

Pathways

Transport
Fatty Acid Oxidation
Reverse Transcription
Vasoconstriction
Ion Transport
Pathogenesis
Hepatocyte Differentiation
Tube Formation
Inflammatory Response
Pressure Natriuresis
Translation
Drug Transport
Regulation Of Ion Transport

Mrna Polyadenylation
Ethanol Oxidation
Hormone Secretion
Regulation Of Blood Pressure
Vasodilation
Cell Proliferation
Dna Repair

PTMs

Hydroxylation
Oxidation

Carboxylation
Reduction

Demethylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP4A11

References

PMID: 7679927 by Palmer C.N.A., et al. Characterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid omega-hydroxylase and the cognate enzyme expressed in Escherichia coli.

PMID: 7798189 by Kawashima H., et al. Purification and cDNA cloning of human liver CYP4A fatty acid omega- hydroxylase.