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- Table of Contents
Facts about Cytochrome P450 2W1.
Furthermore, it is apparently involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). .
Human | |
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Gene Name: | CYP2W1 |
Uniprot: | Q8TAV3 |
Entrez: | 54905 |
Belongs to: |
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cytochrome P450 family |
CYPIIW1; cytochrome P450 2W1; cytochrome P450, family 2, subfamily W, polypeptide 1; EC 1.14.14.-; EC 1.14.14.1; EC 1.14.14.5; FLJ20359; MGC34287
Mass (kDA):
53.844 kDA
Human | |
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Location: | 7p22.3 |
Sequence: | 7; NC_000007.14 (983155..989640) |
Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.
Endoplasmic reticulum lumen. Cell membrane. About 8% are expressed on the cell surface.
PMID: 16426568 by Karlgren M., et al. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.
PMID: 16551781 by Wu Z.L., et al. Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1.