CXADR Antibodies

AND CXADR ELISA kits, CXADR Proteins

Many biological assays use antibodies to detect CXADR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXADR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXADR antibodies...

We validate the specificity of these antibodies to CXADR by testing them on tissues known to express CXADR positively and negatively. Browse below to find the CXADR antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CXADR Infographic by Boster Bio

All CXADR Products

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Product

Figures

Specificity

Applications

Price

Anti-Coxsackie Adenovirus Receptor/CXADR Antibody Picoband®

1 Q&As

Human, Mouse, Rat

$370
Cat # PA1852
100 μg/vial

Mouse CXADR ELISA Kit PicoKine®

9 Q&As

Mouse

ELISA

$499
Cat # EK1725
96 wells/kit, with removable strips.

Rat CXADR ELISA Kit PicoKine®

8 Q&As

Rat

ELISA

$499
Cat # EK1726
96 wells/kit, with removable strips.

Anti-CXADR Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A02747
100ul

Human CXADR Recombinant Protein

SDS-PAGE

$250
Cat # PROTP78310
Starting from 20ug

CXADR (NM_001338) Human Over-expression Lysate

Human

$628
Cat # LS001525
100 µg

Anti-CXADR Antibody Picoband®

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02747-1
100 µg/vial

CXADR Overview

Facts about Coxsackievirus and adenovirus receptor.

CXADR 3D structure. Source: alphafold

Coxsackievirus and adenovirus receptor (CXADR)

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes.

The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases.

Gene Information

Human
Gene Name:	CXADR
Uniprot:	P78310
Entrez:	1525

Family

Belongs to:

No superfamily

Alternative Names

CAR10Coxsackievirus B-adenovirus receptor; CAR4/6; coxsackie virus and adenovirus receptor; coxsackie virus B receptor; coxsackievirus and adenovirus receptor; CVB3 binding protein; CVB3 BP; CVB3-binding protein; CXADR; HCAR; HCVADR

Molecular Weight

Mass (kDA):
40.03 kDA

Genomic Context


Human

Location:	21q21.1
Sequence:	21; NC_000021.9 (17512906..17636213)

Tissue Specificity

Expressed in pancreas, brain, heart, small intestine, testis, prostate and at a lower level in liver and lung. Isoform 5 is ubiquitously expressed. Isoform 3 is expressed in heart, lung and pancreas. In skeletal muscle, isoform 1 is found at the neuromuscular junction and isoform 2 is found in blood vessels. In cardiac muscle, isoform 1 and isoform 2 are found at intercalated disks. In heart expressed in subendothelial layers of the vessel wall but not in the luminal endothelial surface. Expression is elevated in hearts with dilated cardiomyopathy.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell junction, adherens junction. In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions (PubMed:12297051). In airway epithelial cells localized to basolateral membrane but not to apical surface (PubMed:11316797).; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.