Neurofascin Antibodies

Neurofascin (NFASC)

Cell adhesion, ankyrin-binding protein that might be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. .

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Gene Information

Human
Gene Name:	NFASC
Uniprot:	O94856
Entrez:	23114

Family

Belongs to:
immunoglobulin superfamily

Alternative Names

DKFZp686P2250; KIAA0756FLJ46866; neurofascin homolog (chicken); neurofascin homolog; Neurofascin; NF; NFASC; NRCAML

Molecular Weight

Mass (kDA):
150.027 kDA

Genomic Context

Human
Location:	1q32.1
Sequence:	1; NC_000001.11 (204828652..205022822)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.; [Isoform 8]: Cell junction, paranodal septate junction.

Diseases

• Tissue Adhesions
• Nervousness
• Sclerosis
• Multiple Sclerosis
• Demyelination
• Demyelinating Diseases
• Muscular Fasciculation
• Experimental Autoimmune Encephalomyelitis
• Ataxia
• Neuroblastoma
• Nerve Degeneration
• Guillain-barre Syndrome
• Chimera Disorder

• Hypoxia-ischemia, Brain
• Lissencephaly
• Encephalomyelitis
• Autoimmune Reaction
• Polyneuropathy
• Neuronal Migration Disorders
• Trauma, Nervous System

Pathways

• Cell Adhesion
• Localization
• Myelination
• Transport
• Neurogenesis
• Axon Extension
• Cell Proliferation
• Receptor Clustering
• Regeneration
• Rna Interference
• Gephyrin Clustering
• Cell Migration
• Aging

• Proteolysis
• Clustering Of Voltage-gated Sodium Channels
• Schwann Cell Proliferation
• Axon Ensheathment
• Muscle Attachment
• Axon Guidance
• Cell-cell Adhesion

PTMs

• Phosphorylation
• Cleavage

• Deglycosylation
• Glycosylation

• Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFASC

Steven Boster Bio - Best Uses Of The NFASC Marker

In this article, we'll be covering Steven Boster's background, work, and family. We will also discuss Steven's education and how he became a firearms expert. We'll also be discussing His best uses for the NFASC marker. Continue reading to find out more. This Steven Boster bio is a great place to start. Here are a few suggestions:

History of Steven Boster

Steven Boster's story is full of events and landmarks that show his life. Boster was a passionate sports fan who loved his family more that anything. Boster loved NASCAR, and was the first person he called when his car broke down at 2 am. He never missed an appointment, even if it was below freezing. He was generous with his friends and was known to treat them like family.

Steve Boster was a native of Joliet, IL, and he died in Madison, WI. He was a successful manager in the retail sector for many years. He was also a Concordia Hall member from Staunton, VA and a U.S. Army veteran. He is survived 6 grandchildren and 2 daughters, Natosha Poeck and Crystal Boster. He is survived by Jack and Sandra Boster, his brothers, and Lisa Milton, his sister. His family includes many nieces, nephews, and great-grandchildren.

His work

His work with the NFASC Marker identified intercostal nerves of the DRG and confirmed the existence of early clusters. A fluorescent signal running along the axolemma was used to identify hemi or node-like structures. He found that the NFASC marker was also expressed by mice lacking Caspr. These results indicate that the NFASC Marker is involved in the formation and maintenance the hemi- and nodes.

The SEP-Nfasc186's mobility is not affected either by junctional disruption or lateral diffusion. The unmyelinated side does not have an axo-glial junction. SEP -Nfasc186 fluorescence recover is therefore not dependent on the axoglial intersection. However, he did note that FRAP and FLIP resulted in similar fluorescence recovery, as expected.