Catenin alpha-2 Antibodies

AND CTNNA2 ELISA kits, Catenin alpha-2 Proteins

Many biological assays use antibodies to detect Catenin alpha-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Catenin alpha-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Catenin alpha-2 antibodies...

We validate the specificity of these antibodies to Catenin alpha-2 by testing them on tissues known to express CTNNA2 positively and negatively. Browse below to find the CTNNA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CTNNA2 Infographic by Boster Bio

All CTNNA2 Products

Product

Figures

Specificity

Applications

Price

Anti-CTNA2 CTNNA2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05862
100ul

CTNNA2 (NM_004389) Human Over-expression Lysate

Human

$628
Cat # LS001496
100 µg

CTNNA2 Overview

Facts about Catenin alpha-2.

CTNNA2 3D structure. Source: alphafold

Catenin alpha-2 (CTNNA2)

May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during evolution.

Functions in the control of startle modulation. .

Gene Information

Human
Gene Name:	CTNNA2
Uniprot:	P26232
Entrez:	1496

Family

Belongs to:

vinculin/alpha-catenin family

Alternative Names

Alpha-catenin-related protein; cancer/testis antigen 114; CAPRrelated; catenin (cadherin-associated protein), alpha 2; catenin alpha-2; CTNR; DKFZp686H02198

Molecular Weight

Mass (kDA):
105.313 kDA

Genomic Context


Human

Location:	2p12
Sequence:	2; NC_000002.12 (79505054..80648868)

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell projection, axon. Nucleus.

Diseases

Tissue Adhesions
Schizophrenia
Nervousness
Alzheimer's Disease
Congenital Cerebellar Hypoplasia
Primary Familial Dilated Cardiomyopathy
Brain Ischemia
Melanoma
Infarction
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Occlusion, Middle Cerebral Artery

Trauma, Nervous System
Digeorge Syndrome
Malignant Neoplasms
Speech Delay
Neoplasms
Cerebrovascular Accident
Antisocial Personality Disorder

Interacting Proteins

ZNF639

Pathways

Cell Adhesion
Localization
Cell-cell Adhesion
Dna Methylation
Methylation
Pathogenesis
Cell-cell Signaling
Cell Proliferation
Prepulse Inhibition
Startle Response

Regeneration
Neuroprotection
Cytoskeleton Organization
Brain Morphogenesis

PTMs

Methylation

Phosphorylation

Reduction

Research Areas

Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTNNA2

References

PMID: 8432524 by Claverie J.-M., et al. Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin).

PMID: 16182284 by Bogaerts S., et al. Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.