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- Table of Contents
2 Citations 1 Q&As
2 Citations 2 Q&As
Facts about Catenin alpha-1.
Can associate with both E- and N-cadherins. Originally thought to be a stable part of E-cadherin/catenin adhesion complexes and also to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.
Human | |
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Gene Name: | CTNNA1 |
Uniprot: | P35221 |
Entrez: | 1495 |
Belongs to: |
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vinculin/alpha-catenin family |
Alpha E-catenin; alpha-catenin; alpha-E-catenin; alphaE-catenin; cadherin-associated protein; CAP102; catenin (cadherin-associated protein), alpha 1 (102kD); catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha-1; FLJ36832; FLJ52416; Renal carcinoma antigen NY-REN-13
Mass (kDA):
100.071 kDA
Human | |
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Location: | 5q31.2 |
Sequence: | 5; NC_000005.10 (138753386..138935034) |
Expressed ubiquitously in normal tissues.
[Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
PMID: 8404069 by Furukawa Y., et al. Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1).
PMID: 8323564 by Oda T., et al. Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.
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