CROT Antibodies

AND CROT ELISA kits, CROT Proteins

Many biological assays use antibodies to detect CROT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CROT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CROT antibodies...

We validate the specificity of these antibodies to CROT by testing them on tissues known to express CROT positively and negatively. Browse below to find the CROT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CROT Infographic by Boster Bio

All CROT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CROT Antibody

Human, Mouse, Rat

IP, WB

$405
Cat # A09812
100ul

Anti-CROT Antibody

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A09812-1
100ul

CROT (NM_021151) Human Over-expression Lysate

Human

$628
Cat # LS054677
100 µg

CROT Overview

Facts about Peroxisomal carnitine O-octanoyltransferase.

CROT 3D structure. Source: alphafold

Peroxisomal carnitine O-octanoyltransferase (CROT)

Beta-oxidation of fatty acids. The maximum activity concerns the C6 to C10 chain length substrate.

Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl- CoA, to its corresponding carnitine ester. .

Gene Information

Human
Gene Name:	CROT
Uniprot:	Q9UKG9
Entrez:	54677

Family

Belongs to:

carnitine/choline acetyltransferase family

Alternative Names

carnitine O-octanoyltransferase; COTperoxisomal carnitine O-octanoyltransferase; EC 2.3.1; EC 2.3.1.137; peroxisomal carnitine acyltransferase; peroxisomal carnitine octanoyltransferase

Molecular Weight

Mass (kDA):
70.178 kDA

Genomic Context


Human

Location:	7q21.12
Sequence:	7; NC_000007.14 (87345646..87399794)

Subcellular Localizations

Peroxisome.

Diseases

Atherosclerosis
Dyslipidemias
Metabolic Diseases
Cardiovascular Diseases
Malignant Neoplasms
Optic Atrophy
Congenital Cerebellar Hypoplasia
Cerebellar Diseases
Liver Damage
Fibrolamellar Carcinoma
Refsum Disease
Dwarfism

Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Hepatotoxicity
Erythroblastosis
Microcephaly
Leukemia, Experimental
Ankylosing Spondylitis

Pathways

Fatty Acid Oxidation
Transport
Translation
Cholesterol Efflux
Cholesterol Homeostasis
Energy Homeostasis
Transepithelial Transport
Drug Resistance
Fatty Acid Homeostasis
Cell Differentiation

Lipid Homeostasis
Reverse Cholesterol Transport
Cell Growth
Cholesterol Transport
Chromatin Remodeling

PTMs

Oxidation

Carboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CROT

References

PMID: 10486279 by Ferdinandusse S., et al. Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta- oxidation of branched-chain fatty acids.

PMID: 11790793 by Morillas M., et al. Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain.