CREB/ATF bZIP transcription factor (CREBZF)

Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent method.

Also suppresses the HCFC1- dependent transcriptional activation by CREB3 and lowers the amount of CREB3 from the mobile. Willing to down-regulate expression of some cellular genes in CREBZF-expressing cells.