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- Table of Contents
Facts about Coronin-1A.
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Human | |
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Gene Name: | CORO1A |
Uniprot: | P31146 |
Entrez: | 11151 |
Belongs to: |
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WD repeat coronin family |
CLIPINA; clipin-A; CORO1; coronin, actin binding protein, 1A; coronin, actin-binding protein, 1A; coronin-1; coronin-1A; Coronin-like protein A; Coronin-like protein p57; FLJ41407; HCORO1; MGC117380; p57; TACOCLABP; Tryptophan aspartate-containing coat protein
Mass (kDA):
51.026 kDA
Human | |
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Location: | 16p11.2 |
Sequence: | 16; NC_000016.10 (30183410..30189076) |
Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle, phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity).
PMID: 7758584 by Suzuki K., et al. Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif.
PMID: 10338208 by Ferrari G., et al. A coat protein on phagosomes involved in the intracellular survival of mycobacteria.