FICD Antibodies

AND FICD ELISA kits, FICD Proteins

Many biological assays use antibodies to detect FICD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FICD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FICD antibodies...

We validate the specificity of these antibodies to FICD by testing them on tissues known to express FICD positively and negatively. Browse below to find the FICD antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FICD Infographic by Boster Bio

All FICD Products

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Anti-HYPE (FICD) Mouse Monoclonal Antibody [Clone ID: OTI2A11]

Human, Mouse, Rat

$523
Cat # M05249
100 µl

HYPE (FICD) (NM_007076) Human Over-expression Lysate

Human

$628
Cat # LS011153
100 µg

FICD Overview

Facts about Protein adenylyltransferase FICD.

FICD 3D structure. Source: alphafold

Protein adenylyltransferase FICD (FICD)

Protein which can both mediate the addition of adenosine 5'-monophosphate (AMP) to certain residues of target proteins (AMPylation), and also the removal of the identical modification from target proteins (de-AMPylation), depending on the context (By similarity). The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will occur (By similarity).

Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or p - AMPylation of HSPA5/BiP (PubMed:25601083). In unstressed cells, functions as an adenylyltransferase by mediating AMPylation of HSPA5/BiP in'Thr-518', thereby inactivating it (By similarity).

Gene Information

Human
Gene Name:	FICD
Uniprot:	Q9BVA6
Entrez:	11153

Family

Belongs to:

fic family

Alternative Names

AMPylator FICD; EC 2.7.7.n1; FIC domain containing; FIC domain-containing protein; fic S-phase protein cell division homolog; HIP-13; HIP13UNQ3041; huntingtin interacting protein 13; Huntingtin interacting protein E; huntingtin interactor protein E; Huntingtin yeast partner E; Huntingtin-interacting protein 13; Huntingtin-interacting protein E; HYPEadenosine monophosphate-protein transferase FICD; MGC5623