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- Table of Contents
Facts about Collagen alpha-5(VI) chain.
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Human | |
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Gene Name: | COL6A5 |
Uniprot: | A8TX70 |
Entrez: | 256076 |
Belongs to: |
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type VI collagen family |
Collagen alpha-5(VI) chain
Mass (kDA):
289.926 kDA
Human | |
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Location: | 3q22.1 |
Sequence: | 3; NC_000003.12 (130345516..130484846) |
Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level).
Secreted, extracellular space, extracellular matrix. Deposed in the extracellular matrix of skeletal muscle.
PMID: 17850181 by Soederhaell C., et al. Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
PMID: 18276594 by Gara S.K., et al. Three novel collagen VI chains with high homology to the alpha 3 chain.