CNKSR3 Antibodies

AND CNKSR3 ELISA kits, CNKSR3 Proteins

Many biological assays use antibodies to detect CNKSR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNKSR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNKSR3 antibodies...

We validate the specificity of these antibodies to CNKSR3 by testing them on tissues known to express CNKSR3 positively and negatively. Browse below to find the CNKSR3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNKSR3 Infographic by Boster Bio

All CNKSR3 Products

Product

Figures

Specificity

Applications

Price

Anti-CNKSR3 Mouse Monoclonal Antibody [Clone ID: OTI1D7]

Human, Mouse, Rat

IHC, WB

$523
Cat # M13481
100 µl

CNKSR3 (NM_173515) Human Over-expression Lysate

Human

$628
Cat # LS154043
100 µg

CNKSR3 Overview

Facts about Connector enhancer of kinase suppressor of ras 3.

CNKSR3 3D structure. Source: alphafold

Connector enhancer of kinase suppressor of ras 3 (CNKSR3)

Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression.

Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC). .

Gene Information

Human
Gene Name:	CNKSR3
Uniprot:	Q6P9H4
Entrez:	154043

Family

Belongs to:

CNKSR family

Alternative Names

CNK homolog protein 3; CNK3; CNKSR family member 3MAGI1; FLJ31349; membrane associated guanylate kinase interacting protein-like 1; membrane-associated guanylate kinase-interacting protein-like 1; WW and PDZ domain containing 1

Molecular Weight

Mass (kDA):
61.904 kDA

Genomic Context


Human

Location:	6q25.2
Sequence:	6; NC_000006.12 (154387515..154510685, complement)

Subcellular Localizations

Cytoplasm. Apical cell membrane; Peripheral membrane protein.

Diseases

Neoplasm Metastasis
Malignant Neoplasms
Nervousness
Asthma
Respiration Disorders
Tissue Adhesions
Proliferative Inflammatory Atrophy

Hypernatremia
Tissue Damage

Interacting Proteins

Pathways

Transport
Localization
Cell Proliferation
Cell Motility
Ion Transport
Cell Fate Determination
Regulation Of Ion Transport

Nuclear Export

PTMs

Phosphorylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNKSR3

References

PMID: 19567370 by Ziera T., et al. Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.

PMID: 22085542 by Attar M.A., et al. CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.