Claudin-14 Antibodies

AND CLDN14 ELISA kits, Claudin-14 Proteins

Many biological assays use antibodies to detect Claudin-14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Claudin-14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Claudin-14 antibodies...

We validate the specificity of these antibodies to Claudin-14 by testing them on tissues known to express CLDN14 positively and negatively. Browse below to find the CLDN14 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLDN14 Infographic by Boster Bio

All CLDN14 Products

Product

Figures

Specificity

Applications

Price

Anti-CLD14 CLDN14 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06550
100ul

Claudin 14 (CLDN14) (NM_144492) Human Over-expression Lysate

Human

$628
Cat # LS023562
100 µg

CLDN14 Overview

Facts about Claudin-14.

CLDN14 3D structure. Source: alphafold

Claudin-14 (CLDN14)

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. .

Gene Information

Human
Gene Name:	CLDN14
Uniprot:	O95500
Entrez:	23562

Family

Belongs to:

claudin family

Alternative Names

claudin 14; Claudin14; Claudin-14; CLDN14; DFNB29; human CLDN14 gene10claudin-14

Molecular Weight

Mass (kDA):
25.699 kDA

Genomic Context


Human

Location:	21q22.13
Sequence:	21; NC_000021.9 (36460621..36576569, complement)

Tissue Specificity

Liver, kidney. Also found in ear.

Subcellular Localizations

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Diseases

Complete Hearing Loss
Kidney Calculi
Sensorineural Hearing Loss (disorder)
Nephrolithiasis
Nodular Sclerosis Classical Hodgkin Lymphoma
Cytopathic Effect
Nerve Degeneration
Kidney Failure, Chronic
Tissue Adhesions
Atherosclerosis
Hypercholesterolemia
Edema

Cardiovascular Diseases
Tumor Angiogenesis
Endolymphatic Hydrops
Balanced Chromosomal Translocation
Kidney Diseases
Chromosomal Translocation
Chronic Kidney Disease

Pathways

Transport
Brain Development
Ion Transport
Regulation Of Angiogenesis
Angiogenesis
Pathogenesis
Glomerular Filtration

Cell-cell Adhesion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLDN14

References

PMID: 11163249 by Wilcox E.R., et al. Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.

PMID: 12791041 by Uyguner O., et al. Frequencies of gap- and tight-junction mutations in Turkish families with autosomal-recessive non-syndromic hearing loss.