CHST5 Antibodies

AND CHST5 ELISA kits, CHST5 Proteins

Many biological assays use antibodies to detect CHST5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHST5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHST5 antibodies...

We validate the specificity of these antibodies to CHST5 by testing them on tissues known to express CHST5 positively and negatively. Browse below to find the CHST5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHST5 Infographic by Boster Bio

All CHST5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CHST5 Antibody

Human

ELISA, WB

$380
Cat # A10506
100ul

CHST5 (NM_024533) Human Over-expression Lysate

Human

$628
Cat # LS023563
100 µg

CHST5 Overview

Facts about Carbohydrate sulfotransferase 5.

CHST5 3D structure. Source: alphafold

Carbohydrate sulfotransferase 5 (CHST5)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate contributor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of brief carbohydrate substrates.

However, it doesn't transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no action toward keratan.

Gene Information

Human
Gene Name:	CHST5
Uniprot:	Q9GZS9
Entrez:	23563

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5; Carbohydrate Sulfotransferase 5; CHST5; GlcNAc6ST3; gn6st-3; GST4-alpha; hIGn6ST; I-GlcNAc6ST

Molecular Weight

Mass (kDA):
46.161 kDA

Genomic Context


Human

Location:	16q23.1
Sequence:	16; NC_000016.10 (75528530..75536108, complement)

Tissue Specificity

Predominantly expressed in small and large intestines and colon. Weakly expressed in lymphocytes. Not expressed in other tissues. Down-regulated in colonic adenocarcinomas.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein. Golgi membrane, early secretory pathway.

Diseases

Corneal Diseases
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Colonic Neoplasms
Inflammation
Malignant Tumor Of Colon

Malignant Paraganglionic Neoplasm

Pathways

Sulfation
Transport
Cell Division
Cell Proliferation
Drug Transport
Cell Growth

PTMs

Sulphation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHST5

References

PMID: 10491328 by Lee J.K., et al. Cloning and characterization of a mammalian N-acetylglucosamine-6- sulfotransferase that is highly restricted to intestinal tissue.

PMID: 11017086 by Akama T.O., et al. Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene.