Carbohydrate sulfotransferase 5 (CHST5)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate contributor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of brief carbohydrate substrates.

However, it doesn't transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no action toward keratan.