CHST6 Antibodies

AND CHST6 ELISA kits, CHST6 Proteins

Many biological assays use antibodies to detect CHST6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHST6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHST6 antibodies...

We validate the specificity of these antibodies to CHST6 by testing them on tissues known to express CHST6 positively and negatively. Browse below to find the CHST6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHST6 Infographic by Boster Bio

All CHST6 Products

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Specificity

Applications

Price

Anti-CHST6 Antibody

13 Q&As

Human

$360
Cat # A04511
100 µl

Anti-CHST6 Mouse Monoclonal Antibody [Clone ID: OTI1D1]

Dog, Human, Monkey, Mouse

$523
Cat # M04511
100 µl

CHST6 (NM_021615) Human Over-expression Lysate

Human

$628
Cat # LS004166
100 µg

CHST6 Overview

Facts about Carbohydrate sulfotransferase 6.

CHST6 3D structure. Source: alphafold

Carbohydrate sulfotransferase 6 (CHST6)

Sulfotransferase that uses 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea.

Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of long and short carbohydrate substrates that have poly-N- acetyllactosamine structures.

Gene Information

Human
Gene Name:	CHST6
Uniprot:	Q9GZX3
Entrez:	4166

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6; Carbohydrate Sulfotransferase 6; C-GlcNAc6ST; CGn6ST; CHST6; corneal N-acetylglucosamine 6-sulfotransferase; Corneal N-acetylglucosamine-6-O-sulfotransferase; EC 2.8.2; EC 2.8.2.-; EC 2.8.2.17; EC 2.8.2.21; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; GlcNAc6ST-5; gn6st-5; GST4-beta; hCGn6ST; MCDC1; N-acetylglucosamine 6-O-sulfotransferase 5

Molecular Weight

Mass (kDA):
44.099 kDA

Genomic Context


Human

Location:	16q23.1
Sequence:	16; NC_000016.10 (75472042..75495441, complement)

Tissue Specificity

Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Dystrophy
Hereditary Corneal Dystrophy
Macular Corneal Dystrophy
Macular Corneal Dystrophy Type I
Corneal Diseases
Familial Amyloid Polyneuropathy, Type V
Blind Vision
Avellino Corneal Dystrophy
Stromal Corneal Dystrophy
Tyrosine Transaminase Deficiency Disease
Malignant Neoplasms

Granular Corneal Dystrophy
Hereditary Diseases
Keratosis
Keratosis Follicularis
Age Related Macular Degeneration
Amyloidosis

Pathways

Pathogenesis
Sulfation
Localization
Transport
Cell Division
Cell Proliferation
Drug Transport

Glycosylation
Cell Growth

PTMs

Sulphation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHST6

References

PMID: 11017086 by Akama T.O., et al. Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene.

PMID: 11181564 by Hemmerich S., et al. Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.