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- Table of Contents
Facts about Lysophosphatidic acid receptor 3.
Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. .
Human | |
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Gene Name: | LPAR3 |
Uniprot: | Q9UBY5 |
Entrez: | 23566 |
Belongs to: |
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G-protein coupled receptor 1 family |
EDG7; Edg-7; EDG7FLJ98231; GPCR; HOFNH30; LPA-3; LPA3LPA receptor 3; LPAR3; lysophosphatidic acid G-protein-coupled receptor7,LPA receptor EDG7; lysophosphatidic acid receptor 3; Lysophosphatidic acid receptor Edg-7; RP4-678I3
Mass (kDA):
40.128 kDA
Human | |
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Location: | 1p22.3 |
Sequence: | 1; NC_000001.11 (84811601..84893206, complement) |
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
Cell membrane; Multi-pass membrane protein.
PMID: 10488122 by Bandoh K., et al. Molecular cloning and characterization of a novel human G-protein- coupled receptor, EDG7, for lysophosphatidic acid.
PMID: 10727522 by Im D.-S., et al. Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate.