CHRNB3 Antibodies

AND CHRNB3 ELISA kits, CHRNB3 Proteins

Many biological assays use antibodies to detect CHRNB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNB3 antibodies...

We validate the specificity of these antibodies to CHRNB3 by testing them on tissues known to express CHRNB3 positively and negatively. Browse below to find the CHRNB3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRNB3 Infographic by Boster Bio

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Anti-ACHB3 CHRNB3 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06316
100ul

CHRNB3 Overview

Facts about Neuronal acetylcholine receptor subunit beta-3.

CHRNB3 3D structure. Source: alphafold

Neuronal acetylcholine receptor subunit beta-3 (CHRNB3)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

Gene Information

Human
Gene Name:	CHRNB3
Uniprot:	Q05901
Entrez:	1142

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

acetylcholine receptor, neuronal nicotinic, beta-3 subunit; cholinergic receptor, nicotinic, beta 3; cholinergic receptor, nicotinic, beta polypeptide 3; CHRNB3; NAChRB3; neuronal acetylcholine receptor subunit beta-3; Nicotinic Acetylcholine R beta 3

Molecular Weight

Mass (kDA):
52.729 kDA

Genomic Context


Human

Location:	8p11.21
Sequence:	8; NC_000008.11 (42697366..42737407)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Nicotine Dependence
Tobacco Use Disorder
Malignant Neoplasms
Epilepsy
Dizziness
Malignant Neoplasm Of Lung
Epilepsy, Frontal Lobe
Parkinson Disease
Bipolar Disorder
Lung Neoplasms
Schizophrenia
Cholangiocarcinoma

Tobacco Dependence Syndrome
Idiopathic Generalized Epilepsy
Neurodegenerative Disorders
Partial Seizure
Epilepsy, Generalized
Ataxia

Pathways

Response To Nicotine
Chromosome Localization
Localization
Righting Reflex
Social Behavior
Neuron Development
Cellular Response To Nicotine
Sex Determination

Pathogenesis
Reflex

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNB3

References

PMID: 8906617 by Elliott K.J., et al. Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

PMID: 9009220 by Groot Kormelink P.J., et al. Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.