CHRNB1 Antibodies

AND CHRNB1 ELISA kits, CHRNB1 Proteins

Many biological assays use antibodies to detect CHRNB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNB1 antibodies...

We validate the specificity of these antibodies to CHRNB1 by testing them on tissues known to express CHRNB1 positively and negatively. Browse below to find the CHRNB1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRNB1 Infographic by Boster Bio

All CHRNB1 Products

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Anti-ACh beta CHRNB1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A07505
100ul

CHRNB1 Overview

Facts about Acetylcholine receptor subunit beta.

CHRNB1 3D structure. Source: alphafold

Acetylcholine receptor subunit beta (CHRNB1)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

Gene Information

Human
Gene Name:	CHRNB1
Uniprot:	P11230
Entrez:	1140

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

acetylcholine receptor subunit beta; ACHRB; ACHRBSCCMS; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; FLJ57107; nAChRB1; Nicotinic Acetylcholine R beta 1

Molecular Weight

Mass (kDA):
56.698 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (7445061..7457710)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Tobacco Use Disorder
Nicotine Dependence
Myasthenias
Malignant Neoplasms
Neurofibromatosis 1
Carcinoma
Malignant Paraganglionic Neoplasm
Pena-shokeir Syndrome Type I
Pterygium
Myasthenic Syndromes, Congenital
Fetal Diseases

Myasthenia Gravis
Malignant Neoplasm Of Lung
Muscle Contracture
Schizoaffective Disorder
Hydrops Fetalis
Genital Neoplasms, Female

Pathways

Pathogenesis
Reverse Transcription
Response To Nicotine
Somite Development

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNB1

References

PMID: 2740233 by Beeson D.M.W., et al. Nucleotide sequence of human muscle acetylcholine receptor beta- subunit.

PMID: 15609996 by Ellison M., et al. Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes.