CHRNB2 Antibodies

AND CHRNB2 ELISA kits, CHRNB2 Proteins

Many biological assays use antibodies to detect CHRNB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNB2 antibodies...

We validate the specificity of these antibodies to CHRNB2 by testing them on tissues known to express CHRNB2 positively and negatively. Browse below to find the CHRNB2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRNB2 Infographic by Boster Bio

All CHRNB2 Products

Product

Figures

Specificity

Applications

Price

Anti-CHRNB2 Antibody

Human, Mouse, Rat

$405
Cat # A02761
100ul

Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (NM_000748) Human Over-expression Lysate

Human

$628
Cat # LS001141
100 µg

CHRNB2 Overview

Facts about Neuronal acetylcholine receptor subunit beta-2.

CHRNB2 3D structure. Source: alphafold

Neuronal acetylcholine receptor subunit beta-2 (CHRNB2)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. .

Gene Information

Human
Gene Name:	CHRNB2
Uniprot:	P17787
Entrez:	1141

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

Cholinergic Receptor Nicotinic Beta 2 Subunit; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); CHRNB2; EFNL3; NAChRB2; neuronal acetylcholine receptor subunit beta-2; Neuronal Nicotinic Acetylcholine R beta 2; neuronal nicotinic acetylcholine receptor beta 2; Nicotinic Acetylcholine R beta 2

Molecular Weight

Mass (kDA):
57.019 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (154567778..154584708)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Epilepsy
Epilepsy, Frontal Lobe
Nicotine Dependence
Tobacco Use Disorder
Alzheimer's Disease
Schizophrenia
Epilepsies, Partial
Dysequilibrium Syndrome
Nocturnal Epilepsy
Epilepsy, Generalized
Febrile Convulsions
Sleep Disorders

Mental Disorders
Partial Seizure
5,10-methylenetetrahydrofolate Reductase Deficiency
Psychotic Disorders
Epilepsies, Myoclonic
Memory Impairment
Nausea

Interacting Proteins

CHRNA5

Pathways

Pathogenesis
Localization
Chromosome Localization
Synaptic Transmission
Inflammatory Response
Response To Nicotine
Cell Adhesion
Transport
Intracellular Transport
Gene Silencing

Cytokine Production
Brain Morphogenesis
Autophagy
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNB2

References

PMID: 2377478 by Anand R., et al. Nucleotide sequence of the human nicotinic acetylcholine receptor beta 2 subunit gene.

PMID: 8906617 by Elliott K.J., et al. Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.