CHRNA3 Antibodies

AND CHRNA3 ELISA kits, CHRNA3 Proteins

Many biological assays use antibodies to detect CHRNA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNA3 antibodies...

We validate the specificity of these antibodies to CHRNA3 by testing them on tissues known to express CHRNA3 positively and negatively. Browse below to find the CHRNA3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRNA3 Infographic by Boster Bio

All CHRNA3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AChR alpha3 CHRNA3 Antibody

1 Citations

Human, Mouse, Rat

$399
Cat # A01981
100μl

Anti-Nicotinic Acetylcholine Receptor alpha 3/CHRNA3 Antibody Picoband®

1 Citations

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A01981-1
100 μg/vial

Anti-Human CHRNA3 DyLight® 488 conjugated Antibody

Human

Flow Cytometry

$515
Cat # A01981-Dyl488
100 μg/vial

Anti-Human CHRNA3 DyLight® 550 conjugated Antibody

5 Q&As

Human

Flow Cytometry

$515
Cat # A01981-Dyl550
100 μg/vial

Human CHRNA3 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP32297
Starting from 20ug

CHRNA3 Overview

Facts about Neuronal acetylcholine receptor subunit alpha-3.

CHRNA3 3D structure. Source: alphafold

Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

Gene Information

Human
Gene Name:	CHRNA3
Uniprot:	P32297
Entrez:	1136

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

cholinergic receptor, nicotinic, alpha 3; cholinergic receptor, nicotinic, alpha polypeptide 3; CHRNA3; LNCR2; MGC104879; NACHRA3; neuronal acetylcholine receptor subunit alpha-3; neuronal nicotinic acetylcholine receptor, alpha3 subunit; Nicotinic Acetylcholine R alpha 3; Nicotinic Acetylcholine Ra3; PAOD2

Molecular Weight

Mass (kDA):
57.48 kDA

Genomic Context


Human

Location:	15q25.1
Sequence:	15; NC_000015.10 (78593052..78620996, complement)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Nicotine Dependence
Malignant Neoplasm Of Lung
Tobacco Use Disorder
Lung Neoplasms
Chronic Obstructive Airway Disease
Lung Diseases
Lung Diseases, Obstructive
Neoplasms
Dysequilibrium Syndrome
Non-small Cell Lung Carcinoma
Adenocarcinoma

Carcinoma
Malignant Squamous Cell Neoplasm
Pulmonary Emphysema
Epilepsy
Epilepsy, Frontal Lobe
Cholangiocarcinoma

Pathways

Pathogenesis
Cell Proliferation
Dna Methylation
Localization
Methylation
Cell Adhesion
Aging
Response To Nicotine
Chromosome Localization
Habituation
Prepulse Inhibition
Catecholamine Secretion
Dna Repair

Cellular Response To Nicotine
Demethylation
Startle Response
Response To Ethanol
Sensitization
Cell Growth
Angiogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNA3

References

PMID: 2336208 by Fornasari D., et al. Molecular cloning of human neuronal nicotinic receptor alpha 3- subunit.

PMID: 1989896 by Mihovilovic M., et al. Expression of mRNAs in human thymus coding for the alpha 3 subunit of a neuronal acetylcholine receptor.

2 Publications of Boster CHRNA3 Antibodies & ELISA Kits

PubMed ID: 10.3390/md17050256, Cervical Cancer Correlates with the Differential Expression of Nicotinic Acetylc...
PubMed ID: 10.1016/j.ejphar.2019.172674, Identification of nicotinic acetylcholine receptor subunits in different lung ca...

*More publications can be found for each product on its corresponding product page