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- Table of Contents
Facts about Neuronal acetylcholine receptor subunit alpha-2.
Human | |
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Gene Name: | CHRNA2 |
Uniprot: | Q15822 |
Entrez: | 1135 |
Belongs to: |
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ligand-gated ion channel (TC 1.A.9) family |
cholinergic receptor, nicotinic, alpha 2 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal); CHRNA2; neuronal acetylcholine receptor subunit alpha-2; Nicotinic Acetylcholine R alpha 2; Nicotinic Acetylcholine Ra2
Mass (kDA):
59.765 kDA
Human | |
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Location: | 8p21.2 |
Sequence: | 8; NC_000008.11 (27459756..27479285, complement) |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
PMID: 8906617 by Elliott K.J., et al. Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.
PMID: 27493220 by Kouvatsos N., et al. Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound alpha2 homopentamer.