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- Table of Contents
Facts about Cholinephosphotransferase 1.
.
Human | |
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Gene Name: | CHPT1 |
Uniprot: | Q8WUD6 |
Entrez: | 56994 |
Belongs to: |
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CDP-alcohol phosphatidyltransferase class-I family |
Cholinephosphotransferase 1
Mass (kDA):
45.097 kDA
Human | |
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Location: | 12q23.2 |
Sequence: | 12; NC_000012.12 (101697640..101752038) |
Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines.
Golgi apparatus membrane; Multi-pass membrane protein.
PMID: 10893425 by Henneberry A.L., et al. Cloning, genomic organization, and characterization of a human cholinephosphotransferase.
PMID: 16292752 by Sinha Roy S., et al. Inhibition of cholinephosphotransferase activity in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.