CFTR Antibodies

AND CFTR ELISA kits, CFTR Proteins

Many biological assays use antibodies to detect CFTR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CFTR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CFTR antibodies...

We validate the specificity of these antibodies to CFTR by testing them on tissues known to express CFTR positively and negatively. Browse below to find the CFTR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CFTR Infographic by Boster Bio

All CFTR Products

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Product

Figures

Specificity

Applications

Price

Anti-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Monoclonal Antibody

5 Q&As

Human, Mouse

IF, IHC, WB

$486
Cat # M00028
100ug/vial

Anti-CFTR Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A00028
0.1 mg

Anti-CFTR (Phospho-Ser737) Antibody

Human, Mouse, Rat

IHC, WB

$380
Cat # A00028S737
100ul

CFTR Overview

Facts about Cystic fibrosis transmembrane conductance regulator.

CFTR 3D structure. Source: alphafold

Cystic fibrosis transmembrane conductance regulator (CFTR)

Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis (PubMed:26823428). The ion channel is also permeable to HCO(3-); selectivity depends upon the extracellular chloride concentration (PubMed:15010471, PubMed:19019741).

Exerts its role also by regulating the action of other ion channels and transporters (PubMed:12403779, PubMed:22178883, PubMed:22121115, PubMed:27941075). Plays an important role in airway fluid homeostasis (PubMed:16645176, PubMed:19621064, PubMed:26823428).

Gene Information

Human
Gene Name:	CFTR
Uniprot:	P13569
Entrez:	1080

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC35; ABCC7CF; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator (ATP-binding cassettesub-family C, member 7); cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator, ATP-binding cassette(sub-family C, member 7); dJ760C5.1; EC 3.6.3; MRP7EC 3.6.3.49; TNR-CFTR

Molecular Weight

Mass (kDA):
168.142 kDA

Genomic Context


Human

Location:	7q31.2
Sequence:	7; NC_000007.14 (117480025..117668665)

Tissue Specificity

Expressed in the respiratory airway, including bronchial epithelium, and in the female reproductive tract, including oviduct (at protein level) (PubMed:22207244, PubMed:15716351). Detected in pancreatic intercalated ducts in the exocrine tissue, on epithelial cells in intralobular striated ducts in sublingual salivary glands, on apical membranes of crypt cells throughout the small and large intestine, and on the reabsorptive duct in eccrine sweat glands (PubMed:1284548, PubMed:28130590). Detected on the equatorial segment of the sperm head (at protein level) (PubMed:19923167). Detected in nasal and bronchial superficial epithelium (PubMed:15716351). Expressed by the central cells on the sebaceous glands, dermal adipocytes and, at lower levels, by epithelial cells (PubMed:28130590).

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus. The channel is internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane (PubMed:17462998, PubMed:19398555, PubMed:20008117). In the oviduct and bronchus, detected on the apical side of epithelial cells, but not associated with cilia (PubMed:22207244). In Se