CGA Antibodies

Glycoprotein hormones alpha chain (CGA)

Gene Information

Human
Gene Name:	CGA
Uniprot:	P01215
Entrez:	1081

Family

Belongs to:
glycoprotein hormones subunit alpha family

Alternative Names

alpha HCG; CGA glycoprotein hormones, alpha polypeptide; CGA; CG-ALPHA; Chorionic Gonadotropin alpha Chain; FSHA; GPHa; GPHa1; HCG; LHA; TSHA

Molecular Weight

Mass (kDA):
13.075 kDA

Genomic Context

Human
Location:	6q14.3
Sequence:	6; NC_000006.12 (87085498..87095106, complement)

Subcellular Localizations

Secreted.

Diseases

• Pituitary Diseases
• Neoplasm Metastasis
• Infertility
• Malignant Neoplasms
• Neoplasms
• Carcinoid Tumor
• Malignant Neoplasm Of Prostate
• Male Infertility
• Adenoma
• Appendicitis
• Appendiceal Neoplasms
• Benign Prostatic Hypertrophy

• Intestinal Diseases
• Paraganglioma
• Oligospermia
• Pituitary Neoplasms
• Bacterial Infections
• Prostatic Diseases
• Extra-adrenal Paraganglioma

Interacting Proteins

• FSHB

Pathways

• Secretion
• Glycosylation
• Localization
• Spermatogenesis
• Cell Proliferation
• Secondary Growth
• Sertoli Cell Proliferation
• Oocyte Growth
• Ovulation
• Rna Splicing
• Drug Resistance

• Cellular Localization
• Primary Growth
• Hatching
• Estrus
• Hormone Secretion

PTMs

• Glycosylation

• Phosphorylation

• Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CGA

Best Uses Of The CGA Marker From Boster Bio

The Boster Bio Anti CGA Antibody Antibody should be stored in the recommended conditions. The antibody is stable at temperatures of -20C for a year and 4C for a month. Boster Bio Anti CGA Antibody is designed for use with CGA from both humans and mice. It has been tested for its specificity in WB and ELISA.

Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody

A glycoprotein hormone, the luteinizing hormone is a heterodimer that contains a common alpha and unique beta subunits. This gives it biological specificity. It is produced by pituitary cells and promotes female spermatogenesis. It causes the Leydig cells to make testosterone in men. This hormone is essential to normal reproduction. It can also be used to predict ovulation in women, and to increase the chances for insemination among males.

This monoclonal antibody was generated from a mouse. It recognizes CGa by immunohistochemical staining or western blotting. The antibody is stable at -20degC or lower for up to a year after production. It should be kept at 2-8degC, or -20degC. It is best to store the antibody at -20degC. However repeated freeze/thaw cycles may cause it to become damaged. Before you use the solution, make sure it is well diluted. This antibody should not ever be used in diagnostic or treatment trials.

Anti-GlycophorinA/CD235a (Erythrocyte Marker), antibody

This monoclonal antibodies was raised against CD235a a glycoprotein which is found on the surface cells of erythrocytes. The antibody can also detect CD234, which is a marker for erythrocytes. It recognizes CD235a, both human and mouse. It is highly sensitive and specific for this cell marker.

The HIR2 antibodies has been tested against normal human plasma cells and was effective in causing the cell agglutination. The recommended concentration for the antibody is 0.03 ug/test. It should be determined empirically that the cell number is sufficient to achieve the desired specificity and sensitivity. The optimal concentration should be titrated in order to achieve the best results.

The routine method of establishing useful host cells is human embryonic kidney cell culture. The CV1 line was made from monkey kidney cells. It was transformed with SV40 and then transferred to mouse Sertoli cell lines. These were both useful mammalian cell types. Boster Bio has developed a monoclonal antibody that is highly specific and can be used to analyze erythrocytes.

Boster Bio's anti–GlycophorinA /CD235a antibody (Erythrocyte Markers), is a monoclonal anti-Glycophorin antibody that exhibits a chimeric antigen. Monoclonal antibody is a type monoclonal antibody that is made using a hybridoma technique. This antibody also includes CH2 and CH3 domains.

Monoclonal antibody were created using the N12M5I8 S.cerevisiae gene. The N12M5I8 gene sequence was cloned by Hyg R and URA3. The resulting cYAC containing BAC N12M5I8 could then be transformed into E. coli Dh20 cells.

The ZNF268 gene encodes a KRAB containing zinc finger protein. The gene is important for hematopoiesis and has been identified as a tumor-associated antigen in chronic lymphocytic leukemia. Various studies have shown that this gene binds most of the known erythroid genes.

The signal sequence for the effector functions of heterologous antibodies is found in the Fc area. These include Fc receptor binding, CDC, Clq binding and phagocytosis. The Fc-receptor binding sequence of the heterologous antibody is identical to that found in mammalian cells.

Anti-PROM1Antibody Picoband

The Anti-PROM1 Antibody Pico-Band from Boster Bio will help you assess the progression and severity of skin cancers. This monoclonal antibody recognises the human PROM1 gene and has been validated using Western Blot. The product is available in PicoBand and 96 well formats. It should be used in conjunction with the ELISA–PROM1 reagent.

The Boster Bio company was founded in 1993 and specializes in the manufacturing of high-specificity, IHC-optimized polyclonal antibodies and ELISA kits. Recently, Boster Bio has expanded their product offerings to include PCR-related molecular biology products. They offer many services, including free technical assistance and 24 hour support for scientists. Boster Bio not only produces high-quality antibodies but also provides support services for its customers as well as the scientific community.

The Picokine kit enables detection of more than 25 biomarkers. This makes it possible to monitor more than two thousand biological samples with high sensitivity. The Picokine ELISA Kit is supported by excellent technical assistance. Boster's extensive database of references confirms that their products are valid in over 23,000 scientific publications. The Picokine Kit is available for purchase through the Boster Bio website.

Boster Bio's Anti-PROM1 Antibody is a great option for Western Blot analysis. This Rabbit Polyclonal Antibody was produced using human PROM1 as an antigen. It reacts with Rat, Mouse, and Human. Its binding ability makes it an excellent choice for immunofluorescence. The antibody Picoband has been validated for immunohistochemistry, flow cytometry, and WB assays.