CFAP298 Antibodies

AND CFAP298 ELISA kits, CFAP298 Proteins

Many biological assays use antibodies to detect CFAP298, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CFAP298 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CFAP298 antibodies...

We validate the specificity of these antibodies to CFAP298 by testing them on tissues known to express CFAP298 positively and negatively. Browse below to find the CFAP298 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CFAP298 Infographic by Boster Bio

All CFAP298 Products

Product

Figures

Specificity

Applications

Price

CFAP298 (NM_021254) Human Recombinant Protein

$1249
Cat # PROTP57076
20 µg

Anti-CFAP298 Mouse Monoclonal Antibody [Clone ID: OTI2H5]

Human

Flow Cytometry, IF, WB

$523
Cat # M31662
100 µl

CFAP298 (NM_021254) Human Over-expression Lysate

Human

$628
Cat # LS056683
100 µg

CFAP298 Overview

Facts about Cilia- and flagella-associated protein 298.

CFAP298 3D structure. Source: alphafold

Cilia- and flagella-associated protein 298 (CFAP298)

Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Appears to be important for initiation rather than maintenance of cilium motility (By similarity).

Required for proper positioning of the cilium in the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity).

Gene Information

Human
Gene Name:	CFAP298
Uniprot:	P57076
Entrez:	56683

Family

Belongs to:

CFAP298 family

Alternative Names

C21orf48; chromosome 21 open reading frame 48; chromosome 21 open reading frame 59; FLJ20467; FLJ37137; FLJ40247; hypothetical protein LOC56683; kur; kurly

Molecular Weight

Mass (kDA):
33.224 kDA

Genomic Context


Human

Location:	21q22.11
Sequence:	21; NC_000021.9 (32599354..32612871, complement)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization.

Diseases

Ciliary dyskinesia, primary, 26 (CILD26)

PTMs

Phosphoprotein

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CFAP298

References

PMID: 24094744 by Austin-Tse C., et al. Zebrafish ciliopathy screen plus human mutational analysis identifies C21orf59 and CCDC65 defects as causing primary ciliary dyskinesia.

PMID: 29601588 by Cho K.J., et al. ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms.