CEP290 Antibodies

AND CEP290 ELISA kits, CEP290 Proteins

Many biological assays use antibodies to detect CEP290, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP290 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP290 antibodies...

We validate the specificity of these antibodies to CEP290 by testing them on tissues known to express CEP290 positively and negatively. Browse below to find the CEP290 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP290 Infographic by Boster Bio

All CEP290 Products

Product

Figures

Specificity

Applications

Price

Anti-Centrosomal protein of 290 kDa CEP290 Antibody

3 Q&As

Human, Mouse

$399
Cat # A01894-1
100μl

Anti-Centrosomal protein of 290 kDa CEP290 Antibody

1 Q&As

Human, Mouse

ELISA, WB

$335
Cat # A30603
100ul

Anti-CEP290 (F812) Antibody

Human, Mouse, Rat

$405
Cat # A01894
100ul

CEP290 Overview

Facts about Centrosomal protein of 290 kDa.

CEP290 3D structure. Source: alphafold

Centrosomal protein of 290 kDa (CEP290)

Its association with CCP110 is necessary for inhibition of primary cilia formation by CCP110 (PubMed:18694559). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs).

Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins into centrosomes such as of PCM1 (PubMed:24421332). Required for the right localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a part in ciliary transport processes (By similarity).

Gene Information

Human
Gene Name:	CEP290
Uniprot:	O15078
Entrez:	80184

Family

Belongs to:

No superfamily

Alternative Names

BBS14Bardet-Biedl syndrome 14 protein; Cancer/testis antigen 87; centrosomal protein 290kDa; Cep290; CT87JBTS6; FLJ13615; JBTS5CTCL tumor antigen se2-2; KIAA0373FLJ21979; LCA10monoclonal 3H11 antigen; MKS4; Nephrocystin-6; NPHP6centrosomal protein of 290 kDa; POC3 centriolar protein homolog; POC3; prostate cancer antigen T21; rd16,3H11AG; SLSN6nephrocytsin-6,3H11Ag; Tumor antigen se2-2

Molecular Weight

Mass (kDA):
290.386 kDA

Genomic Context


Human

Location:	12q21.32
Sequence:	12; NC_000012.12 (88049013..88142216, complement)

Tissue Specificity

Ubiquitous. Expressed strongly in placenta and weakly in brain.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Nucleus. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasmic vesicle. Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock (PubMed:24121310). Found in the connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells (By