CDC42SE1 Antibodies

AND CDC42SE1 ELISA kits, CDC42SE1 Proteins

Many biological assays use antibodies to detect CDC42SE1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC42SE1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC42SE1 antibodies...

We validate the specificity of these antibodies to CDC42SE1 by testing them on tissues known to express CDC42SE1 positively and negatively. Browse below to find the CDC42SE1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDC42SE1 Infographic by Boster Bio

All CDC42SE1 Products

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Specificity

Applications

Price

CDC42SE1 (NM_020239) Human Recombinant Protein

$1249
Cat # PROTQ9NRR8
20 µg

CDC42SE1 (NM_001038707) Human Over-expression Lysate

Human

$628
Cat # LS056882
100 µg

CDC42SE1 Overview

Facts about CDC42 small effector protein 1.

CDC42SE1 3D structure. Source: alphafold

CDC42 small effector protein 1 (CDC42SE1)

Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, causing actin filament assembly. Alters CDC42-induced cell shape changes.

In activated T-cells, may play a part in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.

Gene Information

Human
Gene Name:	CDC42SE1
Uniprot:	Q9NRR8
Entrez:	56882

Family

Belongs to:

CDC42SE/SPEC family

Alternative Names

1300002M12Rik; CDC42 small effector 1; CDC42-binding protein SCIP1; SCIP1; signaling molecule SPEC1 beta; Small effector of CDC42 protein 1; small protein effector 1 of Cdc42; SPEC1CDC42 small effector protein 1

Molecular Weight

Mass (kDA):
8.925 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (151050971..151059649, complement)

Tissue Specificity

Widely expressed. Expressed at higher level in T-lymphocytes, dendritic and whole blood cells.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Recruited to the activated TCR prior actin polymerization.

Diseases

Stomach Neoplasms
Malignant Neoplasm Of Stomach
Malignant Neoplasms

PTMs

Lipoprotein

Palmitate

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC42SE1

References

PMID: 10816584 by Pirone D.M., et al. SPECs, small binding proteins for Cdc42.

PMID: 11595176 by Pirone D.M., et al. The genomic structure of the human SPEC1 gene reveals complex splicing and close promoter proximity to the AF1q translocation gene.