Endosialin Antibodies

AND CD248 ELISA kits, Endosialin Proteins

Many biological assays use antibodies to detect Endosialin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endosialin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endosialin antibodies...

We validate the specificity of these antibodies to Endosialin by testing them on tissues known to express CD248 positively and negatively. Browse below to find the CD248 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD248 Infographic by Boster Bio

All CD248 Products

Product

Figures

Specificity

Applications

Price

Anti-TEM1 CD248 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A04735
0.1 mg

Anti-Endosialin CD248 Antibody

Human, Mouse, Rat

$405
Cat # A04735-1
100ul

Anti-TEM1 (CD248) Mouse Monoclonal Antibody [Clone ID: OTI1H6]

Human

IHC, WB

$523
Cat # M04735
100 µl

TEM1 (CD248) (NM_020404) Human Over-expression Lysate

Human

$628
Cat # LS057124
100 µg

CD248 Overview

Facts about Endosialin.

CD248 3D structure. Source: alphafold

Endosialin (CD248)

May play a role in tumor angiogenesis. .

Gene Information

Human
Gene Name:	CD248
Uniprot:	Q9HCU0
Entrez:	57124

Family

Belongs to:

No superfamily

Alternative Names

2610111G01Rik; CD164 sialomucin-like 1; CD164L1; CD248 antigen; CD248 antigen, endosialin; CD248 molecule, endosialin; CD248; Endosialin; MGC119479; TEM1; TEM1MGC119478; Tumor endothelial marker 1

Molecular Weight

Mass (kDA):
80.859 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (66314494..66317044, complement)

Tissue Specificity

Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Tumor Angiogenesis
Pathologic Neovascularization
Carcinoma
Malignant Paraganglionic Neoplasm
Inflammation
Tissue Adhesions
Neoplasm Metastasis
Sarcoma
Arthritis
Tumor Progression

Glioblastoma
Brain Neoplasms
Melanoma
Neoplasms, Experimental
Malignant Tumor Of Colon
Fibrosarcoma

Pathways

Angiogenesis
Cell Adhesion
Tube Formation
Localization
Cell Proliferation
Tissue Development
Fibroblast Activation
Sprouting Angiogenesis
Blood Coagulation
Blood Vessel Development
Vasculature Development
Inflammatory Response
Senescence

Regeneration
Replicative Senescence
Chemotaxis
Phagocytosis
Coagulation
Cellular Localization
Tissue Remodeling

PTMs

Phosphorylation

Biotinylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD248

References

PMID: 10947988 by St Croix B., et al. Genes expressed in human tumor endothelium.

PMID: 11084048 by Christian S., et al. Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.