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- Table of Contents
1 Citations 8 Q&As
Facts about C-C motif chemokine 24.
Chemotactic for Napping T-lymphocytes, and eosinophils.
Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes.Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
Human | |
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Gene Name: | CCL24 |
Uniprot: | O00175 |
Entrez: | 6369 |
Belongs to: |
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intercrine beta (chemokine CC) family |
CCL24; chemokine (C-C motif) ligand 24; Ckb-6; Eosinophil chemotactic protein 2; Eotaxin-2; member 24; MPIF2; MPIF-2; MPIF2Myeloid progenitor inhibitory factor 2; MPIF-2Small-inducible cytokine A24; SCYA24CK-beta-6
Mass (kDA):
13.134 kDA
Human | |
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Location: | 7q11.23 |
Sequence: | 7; NC_000007.14 (75810825..75823372, complement) |
Activated monocytes and activated T lymphocytes.
Secreted.
PMID: 9104803 by Patel V.P., et al. Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.
PMID: 9365122 by White J.R., et al. Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils.
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