SDHD Antibodies

AND SDHD ELISA kits, SDHD Proteins

Many biological assays use antibodies to detect SDHD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDHD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDHD antibodies...

We validate the specificity of these antibodies to SDHD by testing them on tissues known to express SDHD positively and negatively. Browse below to find the SDHD antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SDHD Infographic by Boster Bio

All SDHD Products

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Product

Figures

Specificity

Applications

Price

Anti-SDHD Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A01261
0.1 mg

SDHD (NM_003002) Human Over-expression Lysate

Human

$628
Cat # LS006392
100 µg

SDHD Overview

Facts about Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial.

SDHD 3D structure. Source: alphafold

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (SDHD)

Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transfer chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). .

Gene Information

Human
Gene Name:	SDHD
Uniprot:	O14521
Entrez:	6392

Family

Belongs to:

CybS family

Alternative Names

CBT1; CII-4; cybS; PGL; PGL1; QPs3; SDH4; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Succinate dehydrogenase complex subunit D; succinate dehydrogenase complex, subunit D, integral membrane protein; succinate dehydrogenase ubiquinone cytochrome B small subunit; Succinate-ubiquinone oxidoreductase cytochrome b small subunit; Succinate-ubiquinone reductase membrane anchor subunit

Molecular Weight

Mass (kDA):
17.043 kDA

Genomic Context


Human

Location:	11q23.1
Sequence:	11; NC_000011.10 (112086873..112095794)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Paraganglioma
Neoplasms
Pheochromocytoma
Adrenal Gland Neoplasms
Von Hippel-lindau Syndrome
Head And Neck Neoplasms
Malignant Neoplasms
Neurofibromatosis 1
Malignant Paraganglionic Neoplasm
Hereditary Paraganglioma
Multiple Endocrine Neoplasia
Neurofibromatoses
Endocrine Gland Neoplasms

Multiple Endocrine Neoplasia Type 2a
Germline Mutation Abnormality
Carotid Body Paraganglioma
Cell Transformation, Neoplastic
Carcinoma
Extra-adrenal Paraganglioma
Neoplasm Metastasis

Pathways

Pathogenesis
Localization
Transport
Electron Transport
Electron Transport Chain
Angiogenesis
Methylation
Tricarboxylic Acid Cycle
Secretion
Cell Proliferation
Excretion
Response To Hypoxia

Oxygen Homeostasis
Aging
Oxidative Phosphorylation
Translation
Cell Cycle
Oncogenesis
Transposition

PTMs

Methylation
Phosphorylation

Reduction
Oxidation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDHD

References

PMID: 9533030 by Hirawake H., et al. Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23.

PMID: 10482792 by Hirawake H., et al. Characterization of the human SDHD gene encoding the small subunit of cytochrome b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase.