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- Table of Contents
Facts about C-C motif chemokine 23.
This protein can bind heparin. Binds CCR1.
Human | |
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Gene Name: | CCL23 |
Uniprot: | P55773 |
Entrez: | 6368 |
Belongs to: |
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intercrine beta (chemokine CC) family |
CCL23; CCL23/MPIF-1; MPIF1; MPIF-1
Mass (kDA):
13.411 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (36013056..36018179, complement) |
High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
Secreted.
PMID: 9104803 by Patel V.P., et al. Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.
PMID: 9558365 by Youn B.-S., et al. Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1.