Girdin Antibodies

AND CCDC88A ELISA kits, Girdin Proteins

Many biological assays use antibodies to detect Girdin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Girdin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Girdin antibodies...

We validate the specificity of these antibodies to Girdin by testing them on tissues known to express CCDC88A positively and negatively. Browse below to find the CCDC88A antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCDC88A Infographic by Boster Bio

All CCDC88A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Girdin CCDC88A Antibody

Human

IHC

$360
Cat # A03282
100 µl

Anti-Phospho Girdin (Ser1417) CCDC88A Antibody

4 Q&As

Human, Mouse

ELISA, IHC-P, IF (paraffin)

$335
Cat # P03282
100ul

Anti-Girdin CCDC88A Antibody

Human, Mouse

ELISA, IHC-P, IF (paraffin)

$335
Cat # A03282-1
100ul

Anti-Girdin CCDC88A Antibody

Human, Mouse, Rat

ELISA, IF, WB

$449
Cat # A03282-2
0.1 mg

Anti-Phospho-Girdin (S1417) CCDC88A Antibody

Human, Mouse

ELISA, IHC

$380
Cat # A03282S1417
100ul

Anti-CCDC88A Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03282-3
100 µg/vial

CCDC88A Overview

Facts about Girdin.

CCDC88A 3D structure. Source: alphafold

Girdin (CCDC88A)

Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the speed of the process of toddlers integration during adult neurogenesis, including proper neuron placement, dendritic growth and synapse formation (By similarity). Improves phosphoinositide 3-kinase (PI3K)- dependent phosphorylation and kinase activity of AKT1/PKB, but does not have kinase activity itself (By similarity).

Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Critical for the integrity of the actin cytoskeleton and for cell migration (PubMed:16139227).

Gene Information

Human
Gene Name:	CCDC88A
Uniprot:	Q3V6T2
Entrez:	55704

Family

Belongs to:

CCDC88 family

Alternative Names

Akt phosphorylation enhancer; APE; APEGIRDIN; CCDC88A; coiled-coil domain containing 88A; Coiled-coil domain-containing protein 88A; G alpha-interacting vesicle-associated protein; G{alpha}-interacting vesicle-associated protein; Girders of actin filament; Girdin; GIV; GIVFLJ10392; GRDN; GRDNAKT-phosphorylation enhancer; HkRP1; HkRP1Galpha-interacting vesicle-associated protein; Hook-related protein 1; KIAA1212DKFZp686D0630

Molecular Weight

Mass (kDA):
216.042 kDA

Genomic Context


Human

Location:	2p16.1
Sequence:	2; NC_000002.12 (55287817..55419856, complement)

Tissue Specificity

Expressed ubiquitously.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cytoplasmic vesicle. Cell projection, lamellipodium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Localizes to the cytosol in unstimulated cells while EGF stimulation promotes membrane localization and guanine nucleotide exchange factor activity (PubMed:27864364). Localizes to the cell membrane through interaction with phosphoinositides (PubMed:16139227, PubMed:15882442).