Calsequestrin-2 Antibodies

AND CASQ2 ELISA kits, Calsequestrin-2 Proteins

Many biological assays use antibodies to detect Calsequestrin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calsequestrin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calsequestrin-2 antibodies...

We validate the specificity of these antibodies to Calsequestrin-2 by testing them on tissues known to express CASQ2 positively and negatively. Browse below to find the CASQ2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CASQ2 Infographic by Boster Bio

All CASQ2 Products

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Product

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Specificity

Applications

Price

CASQ2 Calsequestrin-2 Dog protein

Rat

$375
Cat # PROTP12637
2ug, 5ug, 10ug

CASQ2 (NM_001232) Human Recombinant Protein

$1249
Cat # PROTO14958
20 µg

CASQ2 (NM_001232) Human Over-expression Lysate

Human

$628
Cat # LS000845
100 µg

CASQ2 Overview

Facts about Calsequestrin-2.

CASQ2 3D structure. Source: alphafold

Calsequestrin-2 (CASQ2)

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and so functions as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues in the protein surface, especially at the interface between subunits.

Can bind around 60 Ca(2+) ions. Regulates the discharge of lumenal Ca(2+) through the calcium release channel RYR2; this plays an important role in triggering muscle contraction.

Gene Information

Human
Gene Name:	CASQ2
Uniprot:	O14958
Entrez:	845

Family

Belongs to:

calsequestrin family

Alternative Names

calsequestrin 2 (cardiac muscle); calsequestrin 2, fast-twitch, cardiac muscle; Calsequestrin, cardiac muscle isoform; calsequestrin-2; FLJ26321; FLJ93514; PDIB2

Molecular Weight

Mass (kDA):
46.436 kDA

Genomic Context


Human

Location:	1p13.1
Sequence:	1; NC_000001.11 (115700021..115768714, complement)

Subcellular Localizations

Sarcoplasmic reticulum lumen. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.