Caspase-14 Antibodies

AND Casp14 ELISA kits, Caspase-14 Proteins

Many biological assays use antibodies to detect Caspase-14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-14 antibodies...

We validate the specificity of these antibodies to Caspase-14 by testing them on tissues known to express Casp14 positively and negatively. Browse below to find the Casp14 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Casp14 Infographic by Boster Bio

All Casp14 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Caspase-14/CASP14 Antibody Picoband®

1 Citations 7 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2104
100 μg/vial

Anti-Caspase-14 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M05143
100 μl

Anti-Caspase-14 CASP14 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A05143
100ul

Caspase 14 (CASP14) (NM_012114) Human Over-expression Lysate

Human

$628
Cat # LS023581
100 µg

Casp14 Overview

Facts about Caspase-14.

Caspase-14 (Casp14)

Non-apoptotic caspase that's involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and is required for cornification (PubMed:18156206).

Regulates maturation of the skin by proteolytically processing filaggrin (PubMed:21654840). In vitro is equally busy on the synthetic caspase substrates WEHD-ACF and IETD-AFC.

Gene Information

Mouse
Gene Name:	Casp14
Uniprot:	O89094
Entrez:	12365

Family

Belongs to:

peptidase C14A family

Alternative Names

apoptosis-related cysteine protease; CASP14; CASP-14; caspase 14, apoptosis-related cysteine peptidase; caspase 14, apoptosis-related cysteine protease; Caspase14; Caspase-14; EC 3.4.22.-; MGC119078; MGC119079; MICE

Molecular Weight

Mass (kDA):
29.458 kDA

Genomic Context


Mouse

Location:	10\|10 C1
Sequence:	10;

Tissue Specificity

Embryo, adult liver and less in adult brain and kidney. Expressed in differentiating keratinocytes of embryonic skin (at protein level). Expressed in keratinocytes of adult skin suprabasal layers (at protein level).

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Psoriasis
Malignant Neoplasm Of Breast
Myeloid Leukemia, Chronic
Myeloid Leukemia
Mammary Neoplasms
Hematologic Neoplasms
Leukemia
Malignant Tumor Of Cervix
Neoplasms, Glandular And Epithelial

Inflammation
Dehydration
Leukemia, Myelocytic, Acute
Malignant Squamous Cell Neoplasm
Cell Transformation, Neoplastic
Skin Neoplasms
Hypertrichosis

Pathways

Cell Death
Keratinocyte Differentiation
Cornification
Programmed Cell Death
Localization
Cell Cycle
Cell Differentiation
Epithelial Cell Differentiation
Keratinization
Hair Follicle Morphogenesis
Hair Follicle Development
Cell Proliferation
Induction Of Apoptosis

Immune Response
Proteolysis
Dna Repair
Cell Cycle Arrest
Senescence
Response To Ionizing Radiation
S Phase

PTMs

Cleavage

Dephosphorylation

Research Areas

Apoptosis
Cancer
Caspases

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Casp14

References

PMID: 9823333 by Ahmad M., et al. Identification and characterization of murine caspase-14, a new member of the caspase family.

PMID: 10203698 by Van de Craen M., et al. Identification of a new caspase homologue: caspase-14.

1 Publications of Boster Caspase-14 Antibodies & ELISA Kits

PubMed ID: 27581210, Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like infl...

*More publications can be found for each product on its corresponding product page